兰索拉唑治疗消化性溃疡54例疗效分析

Clinical analysis of Lansoprazole in treatment of peptic ulcer 54 cases

目的:探讨兰索拉唑片治疗消化性溃疡的临床疗效。方法:将108例消化性溃疡患者随机分为治疗组和对照组各54例,治疗组应用兰索拉唑,对照组应用奥美拉唑,并同时服用阿莫西林和克拉霉素进行治疗,观察并比较两组的临床疗效。结果:治疗组治疗1周时症状缓解情况明显优于对照组,差异具有统计学意义(P<0.05);治疗结束后,两组患者溃疡愈合与Hp根除率等,差异无统计学意义(P>0.05)。结论:兰索拉唑治疗消化性溃疡止痛效应快,临床效果好。

Objective：To observe the clinical efficacy of Lansoprazole in peptic ulcer.Methods：108 patients with peptic ulcer were randomly divided into treatment group and control group,each group had 54 cases.The treatment group re ceived lansoprazole,the control group were treated with omeprazole,meanwhile took amoxicillin and clarithromycin in treatment,the clinical efficacy of two groups were observed and compared.Results：After one week of therapy in treatment group,symptoms relieved better than the control group,there was significant difference between the two groups（P0.05）.After four weeks of trertment,ulcer healing and Hp eradication rate had no significant difference between two groups（P0.05）.Conclusion：Lansoprazole can fast relive peptic ulcer pain and has better clinical effect.