摘要
我们从南海海底沉积环境分离了一株放线菌SCSIO1635,经16S rDNA的序列分析将该株菌鉴定为链霉菌属。我们从该菌的发酵液中分离得到了4个化合物,经质谱和核磁共振波谱解析,确定为抗霉素类化合物:异构体antimycin A1a和A1b(1)、deisovalerylblastmycin(2)、kitamycin A(3)和antimycin A9(4)。
The strain SCSIO 1635 was isolated from marine sediment of the South China Sea,and identified as a member of Streptomyces according to the 16S rDNA sequence. Four compounds were isolated from Streptomyces sp. SCSIO 1635. The compounds were found to be structurally-related to antimyeins by detailed analyses of MS and NMR spectroscopic data ,and were identified as antimyein A1, and A1b （ 1 ）, deisovalerylblastmyein （2）, kitamycin A （3）, and antimyein A9 （4）, respectively.
出处
《天然产物研究与开发》
CAS
CSCD
2011年第1期10-14,42,共6页
Natural Product Research and Development
基金
supported by the Funds of the Chinese Academy of Sciences for Key Topics in Innovation Engineering(KZCX2-YW-216,KSCX2-YW-G-065,KSCX2-YW-G-073)
Natural Science Funds of South China Sea Institute of Oceanology for Young Scholar(SQ200903)
Funds of Frontier Areas of SCSIO (LYQY200805)
Open Project Program of Key Laboratory of Marine Bio-resources Sustainable Utilization(LMB091013)
关键词
南海沉积环境
海洋放线菌
海洋微生物天然产物
链霉菌
抗霉素
marine sediments of South China Sea
marine actinomycetes
marine microbial natural products
Streptomyces
antimycins
