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天冬氨酸氨基转移酶与血小板比值指数在预测慢性乙型肝炎肝纤维化中的临床意义 被引量:2

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摘要 目的 评价天冬氨酸氨基转移酶(AST)与血小板比值指数(APRI)在预测慢性乙型肝炎(CHB)肝纤维化中的临床意义.方法 对156例CHB患者肝组织纤维化程度进行Ishak评分.同时检测AST和血小板,计算APRI.比较不同肝纤维化分期与APRI间的关系.结果 APRI随着肝纤维化程度的升高而升高(P<0.01),28例CHB患者给予抗病毒药物治疗,治疗前APRI为1.391±0.109,治疗后为0.430±0.062,治疗前后比较差异有统计学意义(P<0.01).结论 APRI可作为预测CHB患者发生显著肝纤维化的指标之一,同时可间接对CHB患者抗病毒治疗的肝脏组织学疗效进行评价.
作者 王忠
出处 《中国医师进修杂志》 2011年第1期57-59,共3页 Chinese Journal of Postgraduates of Medicine
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二级参考文献15

共引文献1930

同被引文献23

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