阳离子交换树脂催化合成异丁酸异戊酯

Synthesis of isoamyl isobutyrate by cation exchange resin

以阳离子交换树脂(NKC-9)为催化剂,以异丁酸和异戊醇为原料合成异丁酸异戊酯。考察了原料配比、催化剂用量、带水剂用量、反应时间等因素对反应的影响。通过正交实验确定制备工艺条件:n(异戊醇):n(异丁酸)=2.0:1,NKC-9催化剂用量为异丁酸和正丁醇总质量的5%,m(甲苯):m(异丁酸)=1.9:1,反应温度≤125℃,反应时间3.5h,在该条件下异丁酸的转化率达到99.3%。催化剂重复使用5次后,异丁酸的转化率为96.7%。

Synthesis of isoamyl isobutyrate from isobutyric acid and isoamyl alcohol by cation exchange resin（NKC-9）was studied.The effects of reaction conditions such as mole ratio of isoamyl alcohol to isobutyric acid,NKC-9 catalyst dosage and reaction time were examined.The optimum reaction conditions were：mole ratio of n（isoamyl alcohol） ∶n（isobutyric acid）=2.0 ∶1;cation exchange resin（NKC-9）as catalyst dosage at 5.0% of the total mass of isobutyric acid and isoamyl alcohol;mass ratio of m（toluene） ∶m（isobutyric acid）=1.9 ∶1;reaction temperature,≤125℃;reaction time,3.5 h.Under the above conditions,the conversion rate of isobutyric acid was up to 99.3%.The activity of the catalyst was still 96.7% after its being used for 5 times.