西妥昔单抗在复发性/转移性头颈部鳞癌治疗中的应用
摘要
全球范围内,头颈部鳞癌(headandnecksquamouscellcarcinoma,HNSCC)年发病率超过500000人,占所有恶性肿瘤发病率的5%。烟草、酒精的滥用以及人乳头瘤病毒(HPV)是HNSCC发病的危险因素;HPV相关的HNSCC具有分化低、基底细胞样特征明显和T分期较低的特点,疗效较好,总体生存率较高。
出处
《肿瘤预防与治疗》
2011年第2期117-122,共6页
Journal of Cancer Control And Treatment
参考文献51
-
1D'Souza G,Kreimer AR,Viscidi R,et al.Case-control study of human papillomavirus and oropharyngeal cancer[J].N Engl J Med,2007,356,1944-1956.
-
2Fakhry C,Westra WH,Li S,et al.Improved survival of patients with human papillomavirus-positive head and neck squamous cell carcinoma in a prospective clinical trial[J].J Natl Cancer Inst,2008,100:261-269.
-
3Li S,Schmitz K,Jeffrey P,et al.Structural basis for inhibition of the epidermal growth factor receptor by cetuximab[J].Cancer Cell,2005,7:301-311.
-
4Sigismund S,Woelk T,Puri C.Clathrin-independent endocytosis of ubiquitinated cargos[J].Proc Natl Acad Sci USA,2005,102:2760-2765.
-
5Lopez-Albaitero A,Ferris R.Immune activation by epidermal growth factor receptor specific monoclonal antibody therapy for head and neck cancer[J].Arch Otolaryngol Head Neck Surg,2007,133:1277-1281.
-
6Kurai J,Chikumi H,Hashimoto K.Antibody-dependent cellular cytotoxicity mediated by cetuximab against lung cancer cell lines[J].Clin Cancer Res,2007,13:1552-1561.
-
7Lax I,Fischer R,Ng C,et al.Noncontiguous regions in the extracellular domain of EGF receptor define ligand-binding specificity[J].Cell Regul,1991,2:337-345.
-
8Wanner G,Mayer C,Kehlbach R,et al.Activation of protein kinase C epsilon stimulates DNA repair via epidermal growth factor nuclear accumulation[J].Radiother Oncol,2008,86:383-390.
-
9Chen D,Nirodi C.The epidermal growth factor receptor:a role in repair of radiation-induced DNA damage[J].Clin Cancer Res,2007,13:6555-6560.
-
10Ang KK,Berkey BA,Tu X,et al.Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinoma[J].Cancer Res,2002,62:7350-7256.
-
1贾深汕.上颌窦鳞癌治疗的初步探讨[J].中国肿瘤临床,1990,17(3):162-164. 被引量:13
-
2刘君.紫杉醇联合放射治疗在头颈部鳞癌治疗中的研究新进展[J].国外医学(耳鼻咽喉科学分册),2002,26(1):5-7.
-
3周冕.吸烟与肺癌的研究进展[J].中国肿瘤,1996,5(3):11-13. 被引量:2
-
4陈从新,周天仇.酒精局部注射治疗肝癌[J].安徽医学,1994,15(2):57-57.
-
5邓辉,邱伟,丰靖卿.宫腔镜早期诊断子宫内膜癌26例[J].广东医学,2007,28(12):2063-2063.
-
6横山显,臧钧,吴玉英.酒精与消化道癌[J].日本医学介绍,1997,18(1):3-5.
-
7唐郢,周琦,朱晓玲.新辅助顺铂联合化疗在宫颈鳞癌治疗中的作用[J].癌症进展,2004,2(5):327-330.
-
8伍波,樊友本.我国甲状腺癌治疗现状:不足、不规范和过度并存[J].中华内科杂志,2017,56(1):11-14. 被引量:28
-
9袁立新.世界上,究竟是谁第一个发现了“烟草致癌”[J].科学与生活,2000(1):10-11.
-
10冯晓灵,吴恒举,聂玉萍,侯孟淮,张春香,耿兰溪,徐卫东,石凤娟.无水酒精治疗中晚期肝癌31例报告[J].临床肝胆病杂志,1989,5(1):40-41. 被引量:3