虎兰饮合水律丸治疗肝硬化腹水48例

Clinical Observation on the Effects of TCM Hu Lan Yin and Shui Lv Bolus on 48 Ascites Due to Hepatocirrhosis

[目的]研究中药虎兰饮合水律丸对晚期肝硬化腹水的治疗作用。[方法]选住院85例肝硬化腹水病例,随机分为治疗组48例,西药对照组37例。治疗组根据病人不同的临床特点进行辨证论治用虎兰饮方加减,同时用水律丸口服,对照组常规用螺内酯片、速尿片、双氢克尿塞或利尿合剂等治疗,观察治疗前后腹水变化情况(B超检测),腹围变化,生化检测,TBili,ALT,24h尿量,生活质量变化(腹胀、饮食)等情况。[结果]经4周的治疗,治疗组显效33例,总有效率93.75%。对照组显效18例,总有效率75.68%,两组比较有非常显著性差异(P<0.01)。[结论]虎兰饮合水律丸治疗肝硬化腹水有较好的疗效,其主要作用是扶正祛邪,较快消除腹水,减轻病人的痛苦,且其作用稳定,复发率小,有较好的治疗效果。

[ Objective] To observe the effects of TCM ＂Hu Lan Yin＂ and ＂Shui Lv bolus＂ on the treatment of ascites due to hepatocirrhosis. [ Methods ] 85 cases of ascites due to cirrhosis patients were randomly divided into the control group （n = 37 ） and the treatment group （n = 48 ）. The treatment group were mainly treated with ＂ Hu Lan Yin＂ companded with＂ Shui Lv bolus＂ , and modified by adding or deleting according to the in- dividual ease. The control group were treated with spironolactone tablets, furosemide tablets, hydrocblorothiaz- ide and so on. The clinical symptoms, liver function, abdominal circumference, 24 - hour urine and Quality of Life were observed, compared before and after treatment. [ Results ] After 4 weeks of treatment, the efficiency of the treatment group was 93.75% , had significant difference （ P 〈 0.01 ） than the control group which was 75.68%. [ Conclusion] TCM ＂Hu Lan Yin＂ companded with ＂Shui Lv bolus＂ had a well effect on aseites due to cirrhosis. It can eliminate ascites rapidly, improve symptoms, the role was stability and the recurrence rate was small.