沐舒坦治疗婴幼儿肺炎临床观察

Clinical observation of treating infantile pneumonia with Ambroxol

目的探讨盐酸氨溴索(沐舒坦)静脉推注联合压缩雾化吸入辅助治疗婴幼儿肺炎的临床疗效。方法 120例婴幼儿肺炎患者随机分为治疗组和对照组,两组均在常规抗感染,纠正缺氧、酸碱平衡、电解质紊乱,治疗组将沐舒坦针剂静脉推注联合压缩雾化吸入治疗,而对照组仅予单纯沐舒坦针剂静脉推注治疗。对两组的咳嗽、痰鸣、气促、肺部湿啰音的消失时间及住院时间进行比较。结果治疗组在治疗后痰鸣、肺部湿啰音消失时间及住院时间比对照组短(P<0.05)。治疗组的显效率明显高于对照组,差异有统计学意义(P<0.05)。结论沐舒坦静脉推注联合压缩雾化吸入治疗与单纯沐舒坦静脉推注治疗对婴幼儿肺炎均取得良好的疗效,但沐舒坦静脉推注联合压缩雾化吸入治疗对咳嗽、咳痰症状改善尤为明显,提示沐舒坦压缩雾化吸入治疗对痰液黏稠、排痰困难有着独到的临床效果。

Objective To discuss the clinical effect of Ambroxol intravenous injection with the assistance of compression atomization inhalation to treat infantile pneumonia.Methods 120 infants with pneumonia were randomly divided into treatment group and control group.The two groups were both given treatments of regular anti-infective,correcting hypoxia,acid-base balance correction and electrolyte imbalance.The treatment group was given Ambroxol intravenous injection with the assistance of compression atomization inhalation,while the control group was only given Ambroxol intravenous injection.The duration of curing cough,sputum obstruction,anhelation and lung moist rale and the time of staying in hospital were compared.Results The treatment group had shorter time to recovery from sputum obstruction and lung moist rale as well as a shorter in-hospital time that of the control group does（P0.05）.The total effective was higher in treatment group than control group.The difference was statistically significant（P0.05）.Conclusion Both combination of ambroxol intravenous injection and compression atomization inhalation and mere ambroxol intravenous injection can get good effects on curing infantile pneumonia.However,combination of ambroxol intravenous injection and compression atomization inhalation could improve the symptoms of cough and expectoration significantly,which proves that combination of ambroxol intravenous injection and compression atomization inhalation has special clinical effects to cure thick sputum and difficulty of expectoration.