间苯三酚对产程影响的临床观察

Clinical observation on progress of lobor with phloroglucinol

目的观察产程活跃期人工破膜加静脉注射间苯三酚对产程的影响。方法选择正常初产妇100例随机分成2组:A组50例于活跃期早期人工破膜;B组50例于活跃期早期人工破膜加间苯三酚80 mg静脉注射(时间>2 min);另随机抽取同期产程未做干预的正常初产妇50例作对照组。观察3组的产程变化及母婴情况。结果 3组的总产程差异有统计学意义,活跃期早期人工破膜可加速产程进展(P<0.05);活跃期早期人工破膜加静脉注射间苯三酚可更加有效地加速产程进展(P<0.01)。3组产后出血和新生儿Apgar评分差异无统计学意义。结论活跃期早期人工破膜加静脉注射间苯三酚可有效加速产程进展,减轻分娩疼痛,且对母婴无明显不良影响。

Objective To observe the impact of intravenous injection Phloroglucinol with artificial rupture of membranes during the active phase of labor.Methods 100 normal primiparas were randomly divided into 2 groups：50 patients of A group accepted artificial rupture of membranes in the in the early active period.50 patients of B group accepted artificial rupture of membranes and Phloroglucinol intravenous injection 80 mg（time 2 minutes）in the early active period.Another 50 normal primiparas were random sample as control group,without making early intervention in the same period.The change of progress of labor and situation of infant were observed in three groups.Results Compare the total process,the difference of 3 group was significant.It could accelerate the progress of labor by artificial rupture of membranes in early active period（P0.05）.It would be more effectively to accelerate the progress of labor by artificial rupture of membranes and intravenous injection of Phloroglucinol in early active period（P0.01）.The difference of postpartum hemorrhage and neonatal Apgar score were not statistically significant among the 3 groups.Conclusion It is effective to accelerate the progress and reduce the pain of labor by artificial rupture of membranes and intravenous injection of Phloroglucinol in early active period.And this method will not have adverse effects to mothers and children.