结节性甲状腺肿手术围术期甲状腺激素变化的研究

The research of the thyroid gland hormone changes by nodular golter surgical operation during perioperative period

目的探讨结节性甲状腺肿手术对甲状腺激素的影响。方法选取结节性甲状腺肿患者30例,术前、术中和术后测量甲状腺激素FT3,FT4,T3,T4,TSH,比较术前和术中,术前和术后以及术中和术后甲状腺激素的变化。结果术前FT3,FT4,T3,T4与术中比较,差异有统计学意义(P<0.05),术前FT3,FT4,T3与术后比较,差异有统计学意义(P<0.05),T4变化差异无统计学意义,术中与术后比较,FT3显著下降,FT4显著升高,差异有统计学意义(P<0.05),TSH术前,术中,术后变化差异无统计学意义。结论甲状腺手术能引起甲状腺素发生变化,其变化情况可能对预后有一定指导作用。

Objective To explore the effect of the surgical operation on the thyroid gland hormone.Methods The method selects 30 patients who had nodular golter.Before the operation,during the operation and after the operation measured the thyroid gland hormone FT3,FT4,T3,T4,TSH.Thyroid gland hormone were compared during perioperative period.Results FT3,FT4,T3,T4 were compared before opreration and during operation,there was significant difference（P0.05）.FT3,FT4,T3 compared before opreration and after operation,there was significant difference（P0.05）,T4 varietieses had never statisticsed to learn difference.Compared with during opreration and after operation as a result,the FT3 descended significantly and the FT4 heated up（p0.05）.TSH had never statisticsed to learn difference.Conclusion The thyroid gland surgical operation can result in the changes of thyroid gland hormone,it＇s the variety circumstance might definitely guide a function towards prognosis.