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运动后大鼠与正常大鼠纹状体5-羟色胺阳性细胞的比较研究 被引量:2

Effect of athletics on 5-HT in the corpus striatum of rats
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摘要 目的观察负荷运动后大鼠5羟-色胺阳性反应物的变化。方法用组织化学和图象分析方法观察大鼠纹状体神经原内5羟-色胺阳性细胞的变化。结果负荷运动后大鼠纹状体神经原5-羟色胺细胞免疫反应增强(P<0.01)。结论 5羟-色胺阳性反应物增加这可能与大运动量后躯体运动协调性发生变化有关。 Objective To investigate the relationship between changes of 5-HT and athletics.Methods The morphine dependent model of male rats was athleticed.The alteration of 5-HT and ultrastructure of anterior horn neurous were studied by means of histochemistry and quantitative method of micro-image analysis system were observed morphine dependence rats.Results The average grey value of 5-HT positive reactive product in experimental group was grower than that in control group(P0.01).Conclusion 5-HT may play an important role in maintenance and development of morphine dependence.
作者 李克
出处 《中国实用医药》 2011年第4期48-49,共2页 China Practical Medicine
关键词 运动 5-羟色胺 纹状体 大鼠 Athletics 5-HT Corpus striatum Rat
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  • 1Fuller PM, Saper CB, Lu J. The pontine REM switch: past and present. J Physiol, 2007 ;584:735 -741
  • 2Saper CB, Seammell TE, Lu J. Hypothalamie regulation of sleep and circadian rhythms. Nature, 2005 ;437 : 1257 - 1263
  • 3Boutrel B, Monaca C, Hen R et al. Involvement of 5-HT1A receptors in homeostatic and stress-induced adaptive regulations of paradoxical sleep: studies in 5-HTIA knock-out mice. J Neurosci, 2002 ;22:4686 - 4692
  • 4Morairty SR, Hedley L, Flores J et al. Selective 5HT2A and 5HT6 receptor antagonists promote sleep in rats. Sleep, 2008 ; 31 : 34 - 44
  • 5Verret L, Fort P, Gervasoni D et al. Localization of the neurons active during paradoxical ( REM ) sleep and projecting to the locus coeruleus noradrenergic neurons in the rat. J Comp Neurol, 2006 ; 495:573 - 586
  • 6Harris GC, Wimmer M, Aaton-Jones G. A role for lateral hypothalamic orexin neurons in reward seeking. Nature, 2005 ;437:556 - 559
  • 7Ding YQ, Marklund U, Yuan W et al. Lmxl b is essential for the development of serotonergic neurons. Nat Neurosci, 2003 ;6:933 - 938
  • 8de Lecea L, Kilduf TS, Peyron C et al. The hypocretins:hypothalamus-specific peptides with neuroexcitatory activity. Proc Natl Acad Sci USA, 1998 ;95:322 - 327
  • 9Sakurai T, Amemiya A, Ishii Met al. Orexins and orexin receptors:a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell, 1998 ;92:573 -585
  • 10Mileykovskiy BY, Kiyashchenko LI, Siegel JM. Behavioral correlates of activity in identified hypocretin/orexin neurons. Neuron, 2005 ;46:787 - 798

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