甲型H1N1流感的中医证候特点

TCM Syndrome Characteristics of Type A H1N1 Flu

目的比较甲型H1N1流感与当年普通季节性流感的中医证候特点,指导甲型H1N1流感辨证论治。方法分别收集甲型H1N1流感患者和当年普通季节性流感患者各200例,对甲型H1N1流感患者的一般临床特征和中医证候进行横断面调查,并与普通的季节性流感患者的资料作对比分析。结果甲型H1N1流感组平均体温明显高于普通季节性流感组(P<0.05);两组患者发热、咽痛、肢体困重、头重如裹或头沉、恶风、恶寒寒战、头痛、鼻塞、流涕、口渴的分布频次存在统计学意义(P<0.01)。甲型H1N1流感组患者随着季节的变化,其头重如裹或头沉、肢体困重、恶风、恶寒、寒战比例有所增加,与冬季比较,夏季、秋季均与其有统计学意义(P<0.05或P<0.01)。结论甲型H1N1流感病邪为热毒夹湿,病机特点为热毒挟湿侵犯肺卫,卫气同病,表证短暂,迅速入里。

Objective To compare the TCM syndrome characteristics of Type A H1N1 Flu with those of the ordinary seasonal flu in the same year in order to guide clinical diagnosis and treatment. Methods The data of 200 cases of Type A H1N1 Flu and 200 cases of ordinary seasonal flu in the same year were collected. The cross section investigation on the general clinical manifestations and TCM syndromes of Type A H1N1 Flu cases was carried out and compared with those of ordinary seasonal flu cases for analysis. Results The average body temperature of Type A H1N1 Flu group was significantly higher than that of the ordinary seasonal flu group （P0.05）. There was statistical difference between the two groups in the frequency of symptoms including fever,sore throat,heaviness in extremities,heaviness in the head,aversion to wind and cold,chills,headache,obstruction of nose,running nose,and thirst （P0.01）. With the seasonal change,in the Type A H1N1 Flu group,the rate of heaviness in the head,heaviness in extremities,aversion to wind and cold,and chills increased. There was statistical significance in summer and autumn as compared with winter （P0.05 or P0.01）. Conclusion The causative factor of Type A H1N1 Flu is the pathogenic heat combined with damp,and its pathogenesis is that the damp-heat invades the lung,causing a pathogenic condition in which the lung and defensive qi are both diseased,therefore,the exterior syndrome is so short and the pathogen enters the interior so quickly.