中医药治疗8946例艾滋病患者临床观察

Clinical Observation on 8946 AIDS Cases Treated by Traditional Chinese Medicine

目的观察中医药治疗艾滋病病毒(HIV)感染者及艾滋病(AIDS)患者的临床疗效。方法收集全国17个省(市)、自治区从2004～2009年采用中医药治疗的HIV/AIDS患者8946例,对患者治疗后4个时间点(12、24、36、48个月)的症状体征、证候分布、CD4+计数、治疗情况及病例脱落死亡情况进行观察分析。结果中医药对发热、乏力、气短、咳嗽、纳呆、腹泻、皮疹等症状有明显疗效,其中以乏力改善最为突出。无症状期患者CD4+计数随时间的变化而降低,艾滋病期患者CD4+计数随时的变化而升高,12、24、36、48个月时与治疗初始时比较,差异均有统计学意义(P<0.05或P<0.01)。结论中医药可阶段性地提高和稳定患者免疫功能,改善症状体征,提高其生存质量。

Objective To observe the therapeutic effect of TCM treatment on HIV infected persons and AIDS patients. Methods The 8946 HIV/AIDS patients treated by TCM in the year 2004~2009 were collected. Symptoms and signs,syndrome distribution,CD4 counting,treatment,case-off,and death of the patients were observed and analyzed 12,24,36,and 48 months after treatment. Results TCM treatment was very effective in relieving the symptoms such as fever,asthenia,shortness of breath,loss of appetite,diarrhea,and skin rashes,of which,the improvement of asthenia was most significant. The CD4 counting of the patients in the asymptomatic period decreased along with the time going on,while that of the AIDS patients increased along with the time going on. The difference was statistically significant （P0.05 or P0.01） after 12,24,36,and 48 months treatment as compared with the baseline. Conclusion TCM therapy is able to enhance and stabilize the immunologic function,improve the symptoms and signs,and improve the survival quality of the patients.