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BRAF基因突变与结直肠癌的研究进展 被引量：2

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摘要 结直肠癌是常见的消化道恶性肿瘤之一,在美国每年约有近13万的新发病例,大约56000人死于结直肠癌,是第2位导致癌症死亡的因素。结直肠癌在我国男、女性恶性肿瘤发病率排名中分列第三和第二位。
作者 吴伟 孙文勇
机构地区 浙江省肿瘤医院病理科
出处 《实用医学杂志》 CAS 北大核心 2011年第5期903-905,共3页 The Journal of Practical Medicine
关键词 结直肠癌 BRAF基因突变 消化道恶性肿瘤 女性恶性肿瘤 新发病例 发病率
分类号 R735.3 [医药卫生—肿瘤]
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参考文献23

  • 1Fang J Y,Richardson B C.The MAPK signalling pathways and colorectal cancer[J].Lancet Oncol,2005,(6):322-327.
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同被引文献22

  • 1陶雅军,段世政,张明,刘君慧,吴怡潇,于慧,傅莹.649例大肠癌临床病理特征分析[J].实用肿瘤学杂志,2006,20(6):489-490. 被引量：5
  • 2尹德奎,张红春,马丽霞,齐玉华,岳丽荣.X线、内镜及超声联合应用在直乙肠交界处结肠癌诊断及分期中的价值[J].中国临床医学影像杂志,2007,18(4):296-297. 被引量：2
  • 3Bulun SE. Endometriosis [J]. N Engl J Med, 2009, 360 (3) :268-279.
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  • 5Chen Q, Zhang C, Chen Y, et al. Identification of endometriosis- related genes by representational difference analysis of cDNA [J]. Aust N Z J Obstet Gynaecol,2012,52(2) : 140-145.
  • 6Vinatier D, Orazi G, Cosson M, et al. Theories of endometriosis [J]. Eur J Obstet Gynecol Reprod Biol, 2001,96 (1):21-34.
  • 7Giudice LC, Kao LC. Endometriosis [J]. Lancet, 2004, 364 (9447) : 1789-1799.
  • 8Bukulmez O, Hardy DB, Carr BR, et al. Androstenedione up-regula- tion of endometrial aromatase expression via local conversion to es- trogen: potential relevance to the pathogenesis of endometriosis [J ]. J Clin Endocrinol Metab, 2008,93 (9) : 3471-3477.
  • 9Yoshino O, Osuga Y, Hirota Y, et al. Possible pathophysiological roles of mitogen-activated protein kinases (MAPKs) in endometrio- sis[J]. Am J Reprod Immunol,2004,52(5) :306-311.
  • 10Yamauchi N, Harada T, Taniguchi F, et al. Tumor necrosis factor- alpha induced the release of interleukin-6 from endometriotic stro- mal ceils by the nuclear factor-kappaB and mitogen activated pro- tein kinase pathways [J]. Fertil Steril, 2004, 82 (Suppl 3) : 1023-1028.

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实用医学杂志
2011年 第5期

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