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FLAG方案治疗难治复发急性白血病的疗效 被引量：1

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摘要 我院自2006年8月至2009年8月应用氟达拉滨（Flud）、阿糖胞苷（Ara-C）和粒细胞集落刺激因子（G-CSF）组成的FLAG方案治疗26例难治复发急性白血病患者,取得了较好的疗效，现报告如下。
作者 蒋锐 谢明
机构地区 湖北省荆门市第一人民医院
出处 《实用医学杂志》 CAS 北大核心 2011年第5期926-927,共2页 The Journal of Practical Medicine
关键词 FLAG方案 白血病 临床治疗 疗效
分类号 R733.71 [医药卫生—肿瘤]
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参考文献6

  • 1Jackson G H.Use of fludarabine in the treatment of acute myeloid leukemia[J].Hematol J,2004,5(Suppl l):62-67.
  • 2Gandhi V,Estey E,Keating M J,et al.Fludarabine potentiates metabolism of cytarabine in patients with acute myelogenous leukemia during therapy[J].J Clin Oncol,1993,11(1):116-124.
  • 3张贤,孟凡义,魏永强,徐丹,黄芬,张钰,江千里,徐兵.氟达拉滨联合阿糖胞苷治疗难治、复发急性淋巴细胞白血病25例[J].实用医学杂志,2008,24(16):2863-2864. 被引量：4
  • 4Yamada K,Furusawa S,Saito K,et al.Concurrent use of granulocyte colony-stimulating factor with low-dose cytosine arabinoside and aclarubicin for previously treated acute myelogenous leukemia:a pilot study[J].Leukemia,1995,9(1):10-14.
  • 5Hashmi K U,Khan B,Ahmed P,et al.FLAG-IDA in the treatment of refractory/relapsed acute leukaemias:single centre study[J].J Pak Med Assoc,2005,55(6):234-238.
  • 6Specchia G,Pastore D,Carluccio P,et al.FLAG-IDA in the treatment of refractory / relapsed adult acute lymphoblastic leukemia[J].Ann Hematol,2005,84(12):792-795.

二级参考文献10

  • 1田怀平,卜书红,李方.氟达拉宾的药物学及应用[J].北京医学,2004,26(5):351-353. 被引量：4
  • 2Weiss M A, Aliff T B, Martin M S, et al. A single, high dose of idarubicin combined with cytarabine as induction therapy for adult patients with recurrent or refractory acute lymphoblastic leukemia[J]. Cancer,2002,95 (3):581-587.
  • 3Miyawaki S, Mizoguehi H, Tomonaga M, et al. A phase Ⅱ study with high-dose cytarabine (NS-075) in adult patients with relapsed and refractory acute leukemia [J]. Gan To Kagaku Ryoho, 1998, 25 (14) : 2229-2242.
  • 4Camera A, Annino L, Chiurazzi F, et al. GIMEMA ALL-Rescue 97:a salvage strategy for primary refractory or relapsed adult acute lymphoblastic leukemia [J].Haemat ologi ca, 2004,89 ( 2 ) : 145 - 153.
  • 5Specchia G, Pastore D, Carluccio P, et al. FLAG-IDA in the treatment of refractory/relapsed adult acute lymphoblastic leukemia [J]. Ann Hematol, 2005,84(12) :792-795.
  • 6Horstmann M A, Hassenpflug W A, zur Stadt U, et al. Amsacrine combined with etoposide and high-dose methylprednisolone as salvage therapy in acute lymphoblastic leukemia in children [J]. Haematologica, 2005,90(12) : 1701-1703.
  • 7Yavuz S, Paydas S, Disel U, et al. IDA-FLAG regimen for the therapy of primary refractory and relapse acute leukemia: a singlecenter experience [ J ]. Am J Ther, 2006,13 (5) :389-393.
  • 8Pastore D, Specchia G, Carluccio P, et al. FLAG-IDA in the treatment of refractory/relapsed acute myeloid leukemia:single-center experience [ J ]. Ann Hematol, 2003,82 (4) : 231-235.
  • 9Hashmi K U, Khan B, Ahmed P, et al. FLAG-IDA in the treatment of refractory/relapsed acute leukaemias: single centre study [J]. J Pak Med Assoc, 2005,55 (6) : 234-238.
  • 10Virchis A, Koh M, Rankin P, et al. Fludarabine,cytosine arabinoslde,granulocyte-colony stimulating factor with or without idarubicin in the treatment of high risk acute leukaemla or myelodysplastic syndromes [J ]. Br J Haematol, 2004,127(2 ) : 238-239.

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实用医学杂志
2011年 第5期

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