期刊文献+

氯沙坦钾对白大衣高血压人群靶器官损伤的保护效应 被引量:1

下载PDF
导出
摘要 目的:研究氯沙坦钾对白大衣高血压人群靶器官的保护作用。方法:给予符合白大衣高血压诊断标准的、且存在靶器官损伤的100例患者为期24周的氯沙坦钾干预,比较氯沙坦钾治疗前后各项观测指标的变化,从而了解此药对白大衣高血压患者靶器官是否有保护作用。结果:采用超声心动图测量室间隔及左室后壁、左室重量指数、颈内动脉的阻力指数均较用药前明显减小(P<0.05),EF指数和E/A值却较前明显升高(P<0.01),而对左房和左室内径未见明显改变。结论:氯沙坦钾可明显改善白大衣高血压患者的左室收缩和舒张功能,从而减少了白大衣高血压对这类患者靶器官的损伤效应。
出处 《心血管病防治知识(学术版)》 2011年第1期13-14,16,共3页 Prevention and Treatment of Cardiovascular Disease
  • 相关文献

参考文献4

二级参考文献13

  • 1[1]Noko M, Nomura S, Shimosawa T, et al. Blood pressure biofeedback treatment of white-coat hypertension. J Psychosom Res. 2000, 48 ( 2 ): 161 ~169.
  • 2[2]Martinez M A, Garcia Puig J, Martin J C, et al. Frequency and determinants of white coat hypertension in mild to moderate hypertension: a primary care-based study. Monitorizacion ambularoria de la presion arterial( MAPA)-area 5 working group. Am J Hypertens. 1999,12(3) :251 ~ 258.
  • 3[3]Owens P, Atkins N, Obrien E. Diagnosis of white coat hypertension by ambulatory blood pressure monitoring. Hypertension. 1999, 34 ( 2 ): 267 ~272.
  • 4[4]Palatini P, Mormino P, Santonastaso M, et al. Target-organ damage in stage I hypertensive subjects with white coat and sustained hyperetension: Results from the HARVEST study. Hypertension. 1998,31( 1 ) :57 ~ 63.
  • 5[5]Muscholl M W, Hense H W, Brockel U, et al. Changes in left ventricular structure and function in patients with white coat hypertension: cross sectional survey, BMJ. 1998,317(7158) :565 ~ 570.
  • 6[8]Khattar R S, Senior R, Lahiri A. Cardiovascular outcome in white-coat versus sustained mild hypertension. Circulation. 1998, 98 ( 18 ): 1892 ~1897.
  • 7[9]Soma J, Wideroe T E, Dahl K, et al. Left ventricular systolic and diastolic function assessed with two-dimensional and Doppler echocardiography in"white coat" hypertension. J Am Coll Cardiol. 1996,28( 1 ): 190 ~ 196.
  • 8[10]Strandberg T E, Salomaa V. White coat effect, blood pressure and mortality in men: prospective cohort study. Eur Heart J. 2000,21 ( 20 ): 1714 ~1718.
  • 9[11]Kario K, Shimaka K, Schwartz J E, et al. Silent and clinically overt stroke in older Japanese subjects with white-coat and sustained hypertension. J Cardiol. 2002,39( 1 ): 52 ~ 54.
  • 10[12]Muldoon M F,Nazzaro P,Sutton-Tyrrell K,et al. White-coat hypertension are carotid artery atherosclerosis: a matching study. Arch Inter Med. 2000,160(10): 1507 ~ 1512.

共引文献1

同被引文献12

  • 1朱雅萍,方宁远.药物干预血管紧张素1型受体拮抗剂对老年白大衣高血压靶器官的保护作用[J].中华老年多器官疾病杂志,2005,4(1):59-59. 被引量:2
  • 2Mancia G,Zanehetti A.White-coat hypertension:minomers, misconceptions and misunderstandings. Journal of Hypertension . 1996
  • 3Flores L,Recasens M,Gomis R,et al.Wh coat hypertension in type 1 diabetic patients without nephropathy. American Journal of Hypertension . 2000
  • 4Ribeiro L,Gam a G,Santos A,et a1.Arterial distensibility in subjects with white-coat hypertension with an d without diabetes or dyslipidaemia:comparison with normotensives and sustained hypertensives. Blood Pressure Monitoring . 2000
  • 5Moreira,Alcantara P,Aleantara C,et a1.Cardiac structure and functional alterations in white coat hypertension. American Journal of Hypertension . 2003
  • 6Nakao M,Nomura S,Shimosawa T,et al.Blood pressure biofeedback treatment of white-coat hypertension. Journal of Psychosomatic Research . 2000
  • 7White W B,Schulman P,McCabe E J,et al.Average daily blood pressure, not office blood pressure,determines cardiac function in patients with hypertension. The Journal of The American Medical Association . 1989
  • 8O’Brien E,Asmar R,Beilin L,et al.European Society of Hypertension recommendations for conventional, ambulatory and home blood pressure measurement. Journal of Hypertension . 2003
  • 9Flores L,Recasens M,Gomis R,et al.White coat hypertension in type 1 diabetic patients without nephropathy. American Journal of Hypertension . 2000
  • 10Tsuzuki S,Matoba,Eguchi S , et al.Angiotensin II Type 2 Receptor Inhibits Cell Proliferation and Activates Tyrosine Phosphatase. Journal of Hypertension . 1996

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部