氧气驱动雾化吸入治疗小儿中重度哮喘疗效的Meta分析

Meta-analysis of effect on treatment of acute episode of asthma of infants with oxygen drived nebulizer

目的 探讨治疗儿童哮喘、缓解支气管痉挛,迅速解除缺氧状态的方法,验证氧驱动雾化吸入法的疗效.方法 按照系统评价的要求全面检索了中国数字医院图书馆（www.chkd.cnki.net）、中国医学科学院的中国生物医学文献光盘数据库（CBM disk）,对符合纳入标准的9篇文献共计741例患者进行了Meta分析.结果 氧气驱动雾化吸入治疗显效率及总有效率、临床症状改善均优于超声雾化吸入,两者比较差异有统计学意义（P＜0.01）.结论 氧气驱动雾化吸入治疗中、重度哮喘急性发作是一种快捷、高效的方法.氧驱动雾化吸入疗效优于超声雾化.

Objective To evaluate the clinical effect of the therapy of nebulized oxygen inhalation in infants with asthma. Methods According to the requirements of cochrane systematic review, a thorough literature search was performed among Chinese digital Hospital Library （ www. chkd. cnki. net ） and Chinese Biomedical Literature Disk Database （CBM disk）. A-meta analysis was performed on a total of 741 patients involved in 9 papers which met the inclusion criteria. Results The obvious effective rate, total effective rate and clinical symptom were improved in study group. The difference between the two groups has reached significance （P 〈0. 0l ）. Conclusions Oxygen-driven method inhalation was quick and effective in treating medium and heavy bronchial asthma, Oxygen atomized inhalation was superior to ultrasound inhalation in therapeutic effect.