结直肠非霍奇金淋巴瘤30例分析

Analysis of 30 cases of colorectal non-Hodgkin＇s lymphoma

目的探讨结直肠非霍奇金淋巴瘤的临床特点、诊治及预后。方法回顾性分析1990年1月至2009年12月收治的30例结直肠非霍奇金淋巴瘤的临床资料，应用Kaplan-Meier法、Log-Rank检验对其进行单因素生存预后分析。结果肿瘤大小、有无远处转移和治疗方式是影响病人预后的主要因素（P〈0．01）；性别、年龄、淋巴结有无转移及肿瘤细胞恶性程度不是影响病人预后的独立因素（P〉0．05）。结论结直肠非霍奇金淋巴瘤临床表现与结直肠癌极为相似，缺乏特异性。治疗以手术为主，术后应辅以化疗。

Objective To explore the clinical features, diagnosis, treatment and prognosis of the colorectal non-Hodgkin＇s lymphoma. Methods Clinical data of 30 cases of colorectal non- Hodgkin＇s lymphoma who were diagnosed and treated in Affiliated Hospital of Qingdao University Medical College from Jan. 1990 to Dec. 2009, were analyzed by Kaplan-Meier method and Log-Rank test. Results Tumor size,distant metastasis and the treatment were the main factors of prognosis（P 〈0. 01 ） ;Sex, age, lymph node metastasis and cell malignancy were not the independent prognostic factors（P〉0. 05）. Conclusion The clinical presentation of colorectal non-Hodgkin＇s lymphoma is very similar. Surgery combined with chemotherapy may provide optimal therapy for patients with the colorectal non-Hodgkin＇ s lymphoma.