儿科清洁手术预防性抗菌药物应用情况分析

Application Situation Analysis of Preventive Antibacterial Medicine in Sterile Surgery of Pediatrics Department

目的探讨在院内实施规范化清洁手术预防性抗菌药物使用的可行性、效果及使用的合理性,建立健全院内预防用药规范,达到清洁手术预防抗菌药物应用合理化、规范化。方法回顾性调查2009年全院清洁手术病案696例。结果被调查的病案中抗菌药物使用率96%,术前、术后均预防用药占49.13%;术前仅预防用药一次、术后未用占44.60%。总的预防用药时间<24h 533例,占77.70%。第1代、2代头孢菌素类和青霉素类占88%,均应用单一药物,无联合应用。术后感染率2.01%。结论贯彻《抗菌药物临床应用指导原则》,在院内制定规范化预防用药方案和完善的监督机制,重视外科手术基本原则,是预防性抗菌药物合理应用的关键。

Objective a discussion on the feasibility,effect and using rationality of applying preventive antibacterial medicine in normalization sterile surgery,establishing perfect preventive medication norm for achieving application rationalization and normalization of it.Methods a retrospective investigation of 696 sterile surgeries in the whole hospital in 2009.Results the application rate of antibacterial medicine in medical records is 96%;preventive medication before and after surgery takes up 49.13%;using preventive medicine only one time before surgery;it takes up 44.60% of not using preventive medicine;the total preventive medicine time less than 24 hours.It takes up 77.70% in 533 medical records.The first and second generation cephalosporins and penicillin take up 88% which use single medicine without combination application.The infection rate after surgery is 2.01%.Conclusions to carry out Antibacterial Medicine Clinical Application Instruction Principle,we draft normalization preventive medication plan and perfect supervision mechanism and attach importance to the basic principle of surgery operation,which is the key of preventive antibacterial medicine application.