2400例住院患儿抗菌药物应用调查分析

Antibiotic Use in Hospitalized Children:Investigation and Analysis of 2400 Cases

目的:了解住院患儿抗菌药物应用情况,评价其应用合理性,为合理用药提供参考。方法:每月随机抽查出院归档病历200份,了解抗菌药物使用情况,按合理使用抗菌药物的原则进行考察。结果:在2 400份病历中,使用抗菌药物的有1 795份,抗菌药物使用率达74.8%,其中单一用药者占79.3%,二联用药者占20.7%。使用抗菌药物以头孢菌素类和大环内酯类为主。病原菌检测率达68.7%,检出阳性率为30.9%。结论:我院抗菌药物使用基本符合《抗菌药物临床应用指导原则》的规定,但仍存在一些使用不合理的现象。

OBJECTIVE：To investigate the antibiotic use status in hospitalized children and evaluate its rationality to provide references for rational use of drugs.METHODS：200 filed medical records were sampled randomly monthly for investigation of the antibiotic use in accordance with the principle of rational use of antibacterials.RESULTS：In the 2 400 medical records,1 795（74.8%） had antibiotic use,with single use accounting for 79.3% and combined use of two antibacterials accounting for 20.7%.Cephalosporins and macrolides were the predominantly used antibacterials.The pathogen detection rate was 68.7%,with positive detection rate of 30.9%.CONCLUSION：The antibiotic use in our hospital was basically in line with the ＂Guiding Principles for Clinical Application of Antibacterials＂,however,some irrational phenomena could still be seen.