关节炎丸对佐剂型关节炎大鼠关节的病理研究

Pathological research on Joints of Rat with Adjuvant induced Arthritis

目的:探讨关节炎丸对佐剂型关节炎大鼠关节病理改变的影响。方法:建立佐剂型关节炎大鼠动物模型,从关节肿胀度和病理改变观察关节炎丸的治疗作用。结果:关节炎丸能显著抑制大鼠足趾肿胀度、滑膜、骨和软骨组织的破坏,且其治疗作用呈现一定的量效关系。结论:关节炎丸有消肿和抑制滑膜增生的作用。

Objective：To investigate effect of Arthritis pills on pathological changes of the adjuvant induced arthritis.Methods：The effect of Arthritis pills is evaluated in terms of joint swelling degree and pathological changes on adjuvant induced arthritis rat model. Results：Arthritis pills could significantly reduce swelling of rat toes; prevent destruction of bones,synovial and cartilage. And the effect is dose dependent. Conclusion：Arthritis pills can reduce swelling and inhibit synovial hyperplasia.