自拟中药汤剂及散剂治疗手足口病临床研究

Self-treatment of Chinese Medicine Decoction and Powder of Hand Foot and Mouth Disease

[目的]探讨辨证使用自拟汤剂及散剂治疗手足口病临床疗效。[方法]将180例临床确诊为手足口病患儿随机分为两组,对照组60例予利巴韦林、阿昔洛韦抗病毒治疗。高热患儿予布洛芬混悬液及免疫球蛋白治疗。治疗组在此基础上加用自拟方辨证施治以化湿解毒汤、清热解毒汤,有口腔溃疡及疱疹溃破者外用愈溃散,观察两组临床疗效。[结果]治疗组在发热、皮疹消退时间,疱疹消退时间,转为重症患儿例数,总病程天数方面均优于对照组(P<0.01或P<0.05),两组疗效比较差异也有显著性意义(P<0.01),治疗组明显优于对照组。[结论]运用自拟汤剂及散剂辨证施治手足口病,疗效显著,药剂价廉,无毒副作用,使用方法简便,值得临床推广使用。

[Objective] To investigate the dialectical use decoction and powder to be treated from the hand, foot and mouth disease in clinical efficacy. [ Method] of 180 cases of children diagnosed with HFMD patients were randomly divided into two groups, 60 cases to be ribavirin, acyclovir antiviral therapy. Ibuprofen suspension for fever in children and immune globulin therapy. The treatment group was based on the use self square to dampness Decoction syndrome differentiation, detoxification soup, oral ulcers and herpes ulceration were more external records, the clinical efficacy. ~＂ Result] In fever, rash subsided time, herpes regression time, into the number of children with severe cases, the total number of course days were better than the control group （ P 〈 0.01 or P 〈 0.05 ） , compared two groups also showed significant differences significance （ P 〈 0.01 ） , treatment group was significantly better than the control group. [ Conclusion] The use of self decoction and powder differential treatment of hand, foot and mouth dlsease, a significant effect, the pharmaceutical cheap, non -toxic side effects, easy to use, is worthy of clinical use.