456例小儿轮状病毒肠炎流行病学的临床特征分析

Study on the epidemiology and clinical features of 456 cases of children's rotavirus gastroenteritis

目的调查小儿轮状病毒肠炎的流行状况及其临床特征。方法搜集我院2008年1月～2009年12月儿科门诊、住院患儿粪便标本1126例,采用免疫层析胶体金法检测轮状病毒抗原。结果 1126例中轮状病毒抗原阳性者456例,阳性率40.49%。89.9%的轮状病毒肠炎发生在2岁以下患儿,发病高峰主要集中在10月、11月、12月。男女比例为1.69∶1。结论轮状病毒是昆明地区3岁以下儿童腹泻的主要病原。0～24月龄是轮状病毒的易感人群。秋冬季10月、11月、12月为流行高峰。2岁以下儿童作为重点预防保护对象。

Objective To investigate the epidemic situation and clinical features of rotavirus gastroenteritis among children. Methods Stool samples Were collected from 1126 hospitalized diarrheic children in pediatrics of our hospital from January 2008 to December 2009. Gold immunochromatography assay（GICA）was used to test the antigen of rotavirus. Results Out of 1126 samples investigated, 456 （40.49%）were of positive rotavirus antigen. 89.9% infected children were under the age of two. The peak period mainly occurred in October, November and December. The ratio of infected boys and girls was 1.69 to 1. Conclusion Rotavirus is the main cause of the diarrhea of children who are under 3-year-old in Kunming. 0 to 24 months children are the most infected group.The peak infective period is from October to December.The children under 2-year old should be the subject for prevent and protect.