摘要
用0、1、3、5、8、10、20和40kGy剂量的60Coγ射线对透明质酸溶液进行辐照,研究了辐照对透明质酸分子量、黏度特性及抗氧化性的影响。结果表明:辐照后透明质酸的分子量和黏度特性随剂量的增加而降低;透明质酸对羟自由基(OH.)和超氧阴离子自由基(O2.)的清除率随剂量的增大逐渐减弱,对DPPH.自由基清除作用和还原力逐渐增强;辐照后透明质酸外观品质没有明显的变化,流动性增强;辐照对透明质酸的红外光谱结构没有明显的改变。
Effect of 60↑Co γ-rays irradiation on molecular weight,viscosity and antioxidant of hyaluronic acid（HA） were studied in this research.The results showed that molecular weight and viscosity of irradiated HA decreased,the scavenging ability of hydroxyl radicals（OH·） and superoxide radicals（O2·） weakened gradually with the increasing of irradiation dose.However,the DPPH.scavenging ability and reducing power increased with the increasing of irradiation dose.The quality and appearance of HA did not change significantly after irradiation,but the rheology enhanced.The infrared spectra structure of HA did not show significant change after irradiation.
出处
《核农学报》
CAS
CSCD
北大核心
2011年第1期83-87,共5页
Journal of Nuclear Agricultural Sciences
基金
中国农业科学院院长基金
关键词
透明质酸
辐照
抗氧化
自由基
hyaluronic acid
irradiation
anti-oxidation
free radicals
