中药注射剂不良反应103例分析

Analysis of 103 cases with adverse drug reaction of traditional Chinese medicine injection

目的 了解中药注射剂不良反应的发生情况.方法 对解放军第九八医院不良反应监测中心2009年1至12月收集到的103例中药注射剂不良反应病例报告进行统计和分析.结果 103例中药注射剂不良反应涉及的中药品种有25种;新出现的不良反应有24例,占23.3%;严重的不良反应有10例,占9.7%.不良反应累及10个系统-器官;不良反应发生率老年人最高,为18.5%.结论 中药注射剂在临床应用广泛,应对其不良反应高度重视,提高合理用药水平.

Objective To investigate the incidence rate and manifestation of the adverse drug reactions （ADRs） indueed by traditional Chinese medicinal injections. Methods Totally 103 cases of ADRs induced by traditional Chinese medicinal injections were analyzed statistically. Results Twenty five kinds of traditional Chinese medicinal injections were involved in the total 103 ADR cages. 24 cases（23.30% ）presented with new ADRs, 10cases（9.71% ）presented with serious A DRs. 10 systems-organs were involved. A DRs were mostly seen in aged patients（ 18.45% ）. Conclusion The use of Chinese medicinal iniections is widespread in the clinic. It is important to attach importance to the ADRs caused by which to promote rational drug use.