复方川芎胶囊治疗颈动脉硬化性眩晕的临床观察

目的:评价复方川芎胶囊对颈动脉硬化性眩晕临床疗效的影响。方法:将80例患者随机分为空白组、川芎组,每组40例,空白组只给予常规药物治疗,川芎组在空白组的前提下给于复方川芎胶囊药物治疗。4个月后,对患者颈动脉内膜-中层厚度、血脂、血管内皮生长因子(VEGF)、C反应蛋白(CRP)指标进行比较。结果:两组间各指标差异有统计学意义(P<0.05),第4个月川芎组各指标均有明显改善,有显著统计学意义(P<0.01)。结论:复方川芎胶囊能够有效地减轻颈动脉粥样硬化,并改善血脂、保护血管内皮细胞、抑制炎症因子。

Objective：To determine the clinical effect of Chuanxiong capsule on Carotid atherosclerotic. Methods：80 Patients were divided randomly into 2 groups：control group was only given medicine treatment;Chuanxiong group had medicine treatment and therapy in combination with Chuanxiong capsule.After 4 mothes,The changes of IMT,blood-fat,vascular endothelial growth factor（VEGF）,C reactive protein （CRP）were compared between the groups. Results： It showed a remarkable reduction between the treatment group and the control group （P 〈0.05）,Chuanxiong capsule group showed significant differences between the treatment group and the control group after 4 mothes （P 〈0.01）.Conclusion：Chuanxiong capsule was effectively decreasing the expression of atherosclerotic,improving blood fat and protecting endothelical cell of vessel.