反复性自然流产患者细菌性阴道病及解脲支原体感染状况118例分析

Analysis on infection of bacterial vaginosis and ureaplasma urealyticum with 118 recurrent spontaneous abortion women

目的了解反复性自然流产患者下生殖道细菌性阴道病及解脲支原体感染情况。方法对118例反复性自然流产患者作为实验组及109例有正常妊娠史的健康体检者作为对照组,进行下生殖道细菌性阴道病及解脲支原体感染检测。结果实验组细菌性阴道病感染28例(23.7%),解脲支原体感染49例(41.5%),二者双重感染25例(21.2%);对照组细菌性阴道病感染13例(11.0%),解脲支原体感染22例(20.2%),二者双重感染9例(8.3%),实验组与对照组比较有统计学意义(P<0.05)。自然流产2次患者细菌性阴道病感染16例(21.0%),解脲支原体感染28例(36.8%),二者双重感染15例(19.7%)。自然流产≥3次患者细菌性阴道病感染13例(28.6%),解脲支原体感染21例(50.0%),二者双重感染10例(23.8%)。随着流产次数的增加解脲支原体感染率上升(P<0.05),细菌性阴道病及二者双重感染率也呈上升趋势,但无统计学意义(P>0.05)。结论下生殖道细菌性阴道病及解脲支原体感染与反复性自然流产之间存在一定相关性,孕前检查要重视筛查细菌性阴道病及解脲支原体感染情况。

Objective To study the reproductive tract in patients with recurrent abortion,bacterial vaginosis and ureaplasm urealyticum infection.Methods Collected in June 2006 ~ October 2009 in our hospital prenatal and postnatal care center treatment of 118 cases of patients with recurrent spontaneous abortion as an object of study,a history of normal pregnancy,109 cases of healthy persons as control the crowd,the next reproductive tract bacteria vaginal disease and detection of ureaplasma urealyticum infection.Results Experimental group of bacterial vaginosis infection in 28 cases（23.7%）,ureaplasma urealyticum infection in 49 cases（41.5%）,both co-infection 25（21.2%）;control group,bacterial vaginosis infection in 13 cases（11.0%）,ureaplasma urealyticum infection in 22 cases（20.2%）,both co-infection 9（8.3%）,the experimental group and control group were significant（P〈0.05）.Spontaneous abortion two times in patients with bacterial vaginosis infection in 16 cases（21.0%）,ureaplasma urealyticum infection in 28 cases（36.8%）,both co-infection in 15 cases（19.7%）,spontaneous abortion ≥3 times in patients with bacterial vaginosis infection in 13 cases（28.6%）,ureaplasma urealyticum infection in 21 cases（50.0%）,both co-infection in 10 patients（23.8%）,with the abortion,the increase in the number of ureaplasma urealyticum infection rate increased（P〈0.05）,bacterial vaginosis disease and two dual infections also on the rise,but no statistical significance（P〉0.05）.Conclusion There is a certain correlation between the lower genital tract bacterial vaginosis and ureaplasma urealyticum infection and recurrent spontaneous abortion,pre-pregnancy examination should pay attention to screening for bacterial vaginosis and ureaplasma urealyticum.