孕期体重指数及其增长对血清瘦素水平的影响

Relationship between serum leptin level and body mass index of pregnant women

目的研究孕期妇女体重指数的增加与其血清瘦素水平间的关系。方法将本院产科2008年2月至2010年4月间收治的138例孕妇设为研究组,并选择同期健康体检的正常女性44例为对照组。研究组患者138例按照孕期被分为早中后期三组,每组46例,将各研究组与对照组的体重指数及相应血清瘦素水平进行对比。结果血清瘦素水平三个研究组与正常对照组之间均存在显著统计学差异,且三个研究组间随孕期BMI的增加,其血清瘦素水平逐渐升高。结论孕期妇女由于胎儿的不断生长以及自身营养的摄入,其体重指数BMI不断增加同时血清瘦素水平也不断增高。孕妇在孕期的体重指数增长与血清瘦素水平呈正相关。

Objective To discuss the relationships between serum leptin level and boy mass index of pregnant women.Methods Clinical test and nursing information of 138 pregnant women from Febuary 2008 to April 2010 were retrospectively analyzed.And 44 cases healthy women have been chosen as blank group for comparison.Results 138 cases pregnant women have been divided into 3 groups as different pregnant period（46 cases for each group）.After the comparison,the serum leptin level has statistical difference between control group and blank group.The serum leptin level has statistical difference between three control groups.Conclusion As to pregnant women,with their BMI increasing,the serum leptin will be higher and higher.The reasons are high estrogen level,fat content and LEP secretion increased.So the increasing BMI has positive correlation with serum leptin level during pregnance.