摘要
观察慢性淤胆型肝炎(CCH) 高压氧(HBO) 治疗前后肝组织学结构变化。用纯氧单仓治疗(2.5 MPa,2h/d,10d/cyc,6cyc)10 例CCH,治疗前后肝穿,病理检查。9 例肝细胞和毛细胆管淤胆减轻明显,7 例肝细胞变性坏死,汇管区炎症减轻明显( P< 0 .05) ;3 例肝间质纤维化轻度减轻( P> 0 .05) ;3 例肝脏炎症及纤维化程度改善不明显。HBO治疗CCH 有较好的退黄和减轻肝脏组织结构损伤的作用。
To observe the changes in the liver tissue structures of patients with Chronic Cholestasis Hepatitis(CCH) treated with Hyperbaric Oxygenation(HBO).Ten patients were treated with HBO Dosage was 2.5Mpa,2 hours a day,10 days for one therapeutic course,with 2 days rest,altogether 6 courses.Before and after the treatment,the patients were done liver biopsy for the liver tissue,and were detected with ordinary pathology methods.9patients’ cholestasis were reduced in the liver cells and canaliculars,7 reducted in liver cell degeneration,necrosis and protal area inflammation;There was statistically significаnt(P<0.05).3 redced in liver fibrinoid regeneration,But there wasn’t statistically significnt(P>0.05).3 liver inflammation and fibrinoid regeneration wasn’t changed.HBO has good therapeutic effects on reducing the liver cholestasis and tissue structure injuries.
出处
《临床肝胆病杂志》
CAS
北大核心
1999年第4期234-235,共2页
Journal of Clinical Hepatology
基金
南京市科委跨世纪学科带头人后备人员计划项目
关键词
高压氧
淤胆型肝炎
肝组织学
氧疗
Hyperbaric oxygenation Chronic cholestasis hepatitis Liver tissue structures.