化裁温胆汤对老年急性中风影响的临床研究──附92例临床观察

Clinical Study on Wendan Decoction for Treatment of Acute Apoplexy in the Elderly Observation of 92 Cases

化裁温胆汤对老年急性中风（急性缺血性脑血管病）60例，并设维脑路通对照组32例进行临床研究，取得较好临床疗效。其中，治疗组对中医症状的总有效率为93．33％，改善神经功能缺损的总有效率为83．33％，疗效皆优于对照组（P＜0．01，P＜0.05），其降低全血粘度、血浆粘度及红细胞聚集指数的作用亦较对照组为好，两组间比较有显著性差异（P＜0．05，P＜0．001），并且治疗组能调节血脂代谢紊乱，显著降低甘油三酯水平。研究表明该化裁温胆汤对老年急性中风（急性缺血性脑血管病）具有明显疗效，能显著改善血流变学指标，调节血脉代谢紊乱，其机理有待更进一步探讨。

Objective: To observe the effect of Wendan decoction(WDD) on acute apoplexy of the seniors. Methods: 60 patients in the treatment group received WDD and 32 patients in control group were given venoruton. Results: In treatment group, the remission rate of symptoms was 93. 33% and the improvement rate of defect of nervous function was 83. 33%, higher than those of the control group (P<0.01 , P<0.05 ). The reduction of whole blood viscosity, plasma viscosity and erythrocyte aggregation index in the treatment group were more significant than those of the control group(P<0.05, P<0.001 ). WDD also regulated disturbance of metabolism of blood-lipid and obviously decreased triglyceride levels. Conclusion: WDD has significant effects on acute apoplexy in the elderly and can significantly improve indexes of hemorrheology and regulate disturbance of metabolism of blood-lipid.However, the theraputic mechanism still need further investigation.