摘要
目的:探讨口底癌MSCT灌注成像的可行性,研究口底癌的MSCT灌注特征。方法:19例口底癌患者行MSCT灌注检查,全部为活检或病理证实;分别测量口底癌组织和自身残存正常口底组织的血流量(BF)、血容量(BV)、毛细血管表面通透性(PS)和平均通过时间(MTT)作为灌注指标,比较灌注值差异,以评价口底癌的血流动力学改变及规律性。结果:19例中口底癌组织CT灌注值BF为(118.179±43.968)ml.min-1.100g-1,BV为(5.283±1.519)ml.100g-1,MTT为(3.623±1.159)S,PS为(20.981±6.874)ml.min-1;自身正常口底组织BF为(19.626±7.041)ml.min-1.100g-1,BV为(1.960±0.616)ml.100g-1,MTT为(12.326±5.276)S,PS为(9.026±3.2391)ml.min-1,两组灌注值差异有显著统计学意义(P值均<0.01)。结论:口底癌的MSCT灌注成像方法可行,灌注数据获得简单快捷,能够定量的反映出口底癌的血流灌注变化。
Objective:To evaluate the feasibility of MSCT perfusion in mouth floor carcinoma and to investigate the characterization of mouth floor carcinoma.Methods:19 cases were studied using MSCT perfusion imaging;all patients were confirmed by the biopsy or the pathology.The opposite side of sick or the surviving normal mouth floor tissue was taken as the control group.Results:In mouth floor carcinoma group(n=19),BF,BV,MTT and PS were(118.179±43.968) ml·min^-1·100g^-1,(5.283±1.519) ml·100g^-1,(3.623±1.159) S,and(20.981±6.874) ml·min^-1,Respectively.BF,BV,MTT and PS in the control group were(19.626±7.041) ml·min^-1·100g^-1,(1.960±0.616) ml·100g^-1,(12.326±5.276) S,and(9.026±3.2391) ml·min^-1.The two groups had significant difference(P〈0.01).Conclusion:The method of MSCT perfusion performed in the area of mouth floor carcinoma is feasible,which is fast and easily to obtain data about perfusion parameters of this areas cancer.
出处
《医学影像学杂志》
2011年第2期186-189,共4页
Journal of Medical Imaging
基金
十堰市科学技术研究与开发计划项目(2009s22)
关键词
口底癌
体层摄影术
X线计算机
灌注
Floor of mouth carcinoma/tomour
Tomography
X-ray computed
Perfusion