藏药螃蟹甲镇咳祛痰平喘有效部位研究

Studies on the effective parts to relieve cough,reduce phlegm and appease asthma from Radix Phlomii

目的:对藏药螃蟹甲的镇咳祛痰平喘作用的有效部位进行筛选。方法:运用小鼠氨水引咳法、小鼠呼吸道酚红排泌法、豚鼠组胺致喘法3个药理实验对螃蟹甲不同提取部位的主要药理学指标进行了考察。结果:螃蟹甲的乙酸乙酯部位和正丁醇部位均有较好的镇咳祛痰平喘作用,其中镇咳、祛痰作用以正丁醇部位为佳,平喘作用以乙酸乙酯部位作用明显。结论:乙酸乙酯部位和正丁醇部位为螃蟹甲镇咳、祛痰、平喘的主要有效部位。

Objective： To search on the effective parts to relieve cough,reduce phlegm and appease asthma from Radis Phlomii.Methods： The major indexes of Radis Phlomii different extraction sites were studied pharmacology through three pharmacodynamic experiments.Results： The acetic acid ethyl ester part and the n-butyl alcohol part of Radis Phlomii had prominent biological activities of relieving cough,reducing phlegm and appeasing asthma.Conclusion： These results showed that the acetic acid ethyl ester part and the n-butyl alcohol part of Radis Phlomii are the effective parts.