BILT肝病治疗仪治疗非酒精性脂肪性肝病32例

Efficacy of the‘Medical Instrument on Hepatic Diseases of DSG Type'in the treatment of patients with nonalcoholic fatty liver disease:an analysis of 32 cases

目的:评估BILT肝病治疗仪(DSG型生物信息红外肝病治疗仪)治疗非酒精性脂肪性肝病(NAFLD)的临床疗效.方法:使用BILT肝病治疗仪治疗NAFLD患者共32例,治疗时间为30min/次,每天2次,上午下午各1次,于治疗前、治疗第4、8、12周分别检查血脂及肝功能(包括TG、TC、HDL、LDL、ALT、AST、GGT、SB、DB),于治疗前、治疗结束时进行上腹部CT平扫,测定肝、脾CT值,计算肝/脾CT比值,观察生化、血脂和影像学改变.结果:与治疗前相比,影像学在治疗后肝/脾C T值显著增加(0.85±0.20v s0.70±0.22,P<0.01).血清学肝功能ALT、AST、GGT、SB、DB显著降低(71.00IU/L±77.60IU/L vs102.93IU/L±54.60IU/L;34.10IU/L±29.42IU/L vs51.37IU/L±18.64IU/L;50.56IU/L±45.36IU/L vs73.33IU/L±45.21IU/L;16.59μmol/L±5.05μmol/L vs20.28μmol/L±9.95μmol/L;4.28μmol/L±1.17μmol/L vs4.99μmol/L±1.93μmol/L;均P<0.05),在基线异常组中,ALT、AST、GGT、SB同样下降明显(P<0.05),仅DB无统计学意义;血脂指标中,治疗后HDL的升高有统计学意义(P<0.01),在基线异常组中变化无统计学意义,TC和LDL仅在基线异常组有明显降低(P<0.05),而对TG改善不明显.结论:BILT肝病治疗仪对NAFLD具有一定疗效.

AIM：To investigate the therapeutic effects of the ＇Medical Instrument on Hepatic Diseases of DSG Type＇in the treatment of patients with nonalco-holic fatty liver disease（NAFLD）.METHODS：Thirty-two NAFLD patients were enrolled in the study.All patients were treated with the＇Medical Instrument on Hepatic Dis-eases of DSG Type＇for 30 min each time,twice daily（one on the morning and the other on the afternoon）.Serum levels of TG,TC,HDL,LDL,ALT,AST,GGT,STB,and DB were evaluated before the treatment and at 4,8,and 12 wk after the treatment.An abdominal CT scan was per-formed before and after the treatment.RESULTS：After treatment,the liver/spleen CT ratio increased significantly（0.85±0.2 vs 0.7±0.22,P0.01）;serum levels of ALT,AST,GGT,SB,and DB decreased markedly（71.00 IU/L±77.60 IU/L vs 102.93 IU/L±54.60 IU/L;34.10 IU/L±29.42 IU/L vs 51.37 IU/L±18.64 IU/L;50.56 IU/L±45.36 IU/L vs 73.33 IU/L ±45.21 IU/L;16.59μmol/L±5.05μmol/L vs 20.28μmol/L±9.95μmol/L;4.28μmol/L± 1.17μmol/L vs 4.99μmol/L±1.93μmol/L,all P0.05）;and serum level of HDL increased significantly（P0.05）.Decreased levels of ALT,AST,GGT,and SB were also noted in patients with abnormal baseline values.Additionally,the treatment significantly decreased serum levels of TC and LDL in patients with abnormal baseline values（both P0.05）,but had no significant im-pact on TG level.CONCLUSION：Treatment with the＇Medical In-strument on Hepatic Diseases of DSG Type＇can improve NAFLD.