期刊文献+

老年人急性冠脉综合征与同型半胱氨酸水平的研究

下载PDF
导出
摘要 目的:探讨老年人血清同型半胱氨酸(HCY)水平与急性冠脉综合征(ACS)的关系。方法:采用循环酶法分别测定老年ACS患者(95例)及对照组(90例)血清中HCY水平。结果:ACS组血清HCY水平明显高于对照组,不同临床类型患者,HCY水平AMI>UAP>对照组。其中AMI老年男性组与对照组比较P<0.01,UAP老年男性组与对照组比较P<0.01;SAP老年女性组与对照组比较P<0.05,AMI老年女性组与对照组比较P<0.01。结论:老年人ACS患者血清HCY水平明显升高,AMI的较UAP的更高,提示HCY水平变化与ACS的发生、发展密切相关,是ACS的一个危险因素。
出处 《吉林医学》 CAS 2011年第5期857-858,共2页 Jilin Medical Journal
  • 相关文献

参考文献6

  • 1Chambers J C,Obeid O A,Refsum H.Plasma homocysteine concentrations and risk of eomrm.ry heart disease in U K Indifin:Asisn and European men[J].Lancet,2000,355:523-527.
  • 2Meer K,Stam F,Guldener C.Homocysteinemia and cardiovascular disease[J].Am J Clin Nulr,2001,73:992-993.
  • 3Chambers J C,Wander G S,Kooner J S.Lowering bloodhomocysteine with folic acid based supplements:meta-analysis ofrandomised trials[J].Indian Heart J.2000,52:59-64.
  • 4Panagi otakos DB,Pit SaVes C,Zeimbekis A,et al.The association be-twecnlifestyle relatedfactorsand plasma homocysteinelevels in healthyindividuals from the'ATITCA'Study[J].1nt J of Cardiol,2005,98(3):471.
  • 5Obaidi AI,Stubbs P,Amersey R,et al.Acute and onvalescent changes in plasma homocysteine concentrations in acutecoronary syndromes[J].Heart,2001,85(4):380-384.
  • 6薛莉,陈树兰,张建荣.高同型半胱氨酸血症对急性冠状动脉综合征患病的作用及其机制探讨[J].中国循环杂志,2002,17(3):183-185. 被引量:25

二级参考文献11

  • 1李健斋.血脂测定技术及其标准化的建议[J].中华心血管病杂志,1997,25(3):172-173.
  • 2[1]Nomenclature and criteria for diagnosis of ischemia heart disease.Report of the hoint international society and federation of cardiology/world health organization task force on standardization of clinical nomenclature.Circulation,1979,59∶607-609.
  • 3[3]Wilcken DEL, Wilcken B.The pathogenesis of coronary artery disease:a possible role for methionine metabolism.J Clin Invest,1976,57∶1079-1082.
  • 4[4]Vane JR.The role of vascular endothelial cells.N Engl J Med,1990,323∶27-36.
  • 5[5]Harbrecht BG, Stadler J, Demetris AJ, et al. Nitric oxide andprostaglandins interact to prevent hepatic damage during murine endo-toxemia.Am J Physiol,1994,266(6 pt 1)∶G1004-1010.
  • 6[6]Jones BG,Rose FA,Tudball N,et al.Lipid peroxidation and homocys-teine induced toxicity.Atherosclerosis,1994,105∶165-170.
  • 7[7]Blundell G, Jones BG,Rose FA,et al.Homocysteine mediated endothelial cell toxicity and its amelioration.Atherosclerosis,1996,122∶163-172.
  • 8[9]Haynes WG,Strachan FE,Webb DJ.Endothelin ETA and ETB recep-tors cause vasoconstriction of human resistance and capacitance vessels in vivo.Circulation,1995,92∶357-363.
  • 9[10]Chua BH,Krebs CJ,Chua CC,et al.Endothelin stimulaters protein synthesis in smooth muscle cells.Am J Physiol,1992,262∶E412-416.
  • 10[11]Harrison DG.From isolated vessels to the catheterization laboratory.Studies of endothelial function in the coronary circulation of humans.Circulation,1989,80∶703-706.

共引文献24

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部