低分子肝素应用于妊娠期肾病综合征的疗效观察

Therapeutic Effect Observation of Low Molecular Heparin Applied to Dropsical Nephritis in Gestational Period

目的:探讨低分子肝素对妊娠期肾病综合征的临床疗效。方法:将52例妊娠期肾病综合征病人随机分为2组,一组加用低分子肝素治疗,另一组作为对照,观察2组病人24h尿蛋白定量、新生儿出生体重及Apgars评分情况。结果:2组病人尿蛋白定量、新生儿出生体重及Apgars评分均有显著差异(P<0.01)。结论:低分子肝素治疗妊娠期肾病综合征可明显降低尿蛋白定量,提高新生儿出生体重及Apgars评分。

Objective：To observe curative effect of low molecular heparin used to dropsical nephritis in gestational period.Methods：52 patients of dropsical nephritis in gestational period were randomly divided into two groups.one group was treated by low molecular heparin,and the other group was contrast control.24 hours urine protein quantitation,brepho-birth weight and Apagers＇ mark were observed.Results：There are significant deviation between the two groups of 24 hours urine protein quantitation,brepho-birth weight and Apagers＇ mark（P0.01）.conclusion：Low molecular hephritis may obviously cut down urine protein quantitation,raise brepho-birth weight and Apagers＇ mark.