COPD患者急性发作期甲状腺激素水平检测的临床意义

Clinic Significance of the Detection of Thyroid Hormone in COPD Patients

目的:探讨COPD患者急性发作期甲状腺激素水平的变化及临床意义。方法:应用免疫化学发光法对156例COPD患者和102例健康者进行甲状腺激素水平的检测并对数据进行分析。结果:COPD缓解期患者甲状腺激素水平与对照组比较,差异无显著性。急性发作期患者甲状腺激素TT3、FT3、TT4、FT4和TSH水平与对照组比较均降低,差异有显著性(P<0.05),缓解期患者与急性发作期患者比较,差异有显著性(P<0.05)。结论:COPD患者急性发作时,血清甲状腺激素水平出现异常,其甲状腺激素水平高、低与COPD患者严重性、病情进展和预后有一定关系。

Objective：To explore the clinic significance of thyroid hormone in COPD patients.Methods：The levels of thyroid hormone were detected in 156 patients with COPD and 102 controls by immune chemiluminescence method.The data was statistically analyzed.Results：Compared with control group,the levels of thyroid hormone were no significanct in remission of COPD（P0.05）.But in acute period,the levels of TT3,TT4,FT4 and TSH decreased.It was significant compared with the control group（P0.05）.Conclusion：The level of serum thyroid hormone changes in an acute attack of COPD,which is particularly concerned with disease progression and prognosis of COPD.