2型糖尿病大血管病变患者中医证候特点的研究

Study on characteristic of symptom and sign of traditional Chinese medicine in type 2 diabetes mellitus combined with macrovascular complication

目的探讨2型糖尿病（T2DM）大血管并发症患者中医证候特点。方法将60例T2DM大血管病变患者按中医证候分为阴虚燥热、气阴两虚、阴阳两虚3组,观察舌象和脉象以及病程和中医证候之间的关系。结果 T2DM大血管病变患者发病年龄50~70岁以阴虚燥热者为多,70岁以上以阴阳两虚为主。病程各组之间无显著性差异,3~5 a者居多。阴虚燥热组以舌红、苔黄燥、脉弦数为主,气阴两虚组以舌红、苔少、脉濡细数为主,阴阳两虚组以舌淡胖、苔白腻、沉迟脉细为主。结论 T2DM大血管病变患者的舌象脉象均符合中医基础理论对证候的认识。用客观的方法分析中医证候之间的区别与联系,可以更好地认识中医证候的本质。

Objective It is to study the characteristic of symptom and sign of traditional Chinese medicine（TCM） in type 2 diabetes mellitus（T2DM） combined with macrovascular complication.Methods 60 patients with T2DM combined with macrovascular complication were divided into dryness-heat due to Yin deficiency group,deficiency both Qi and Yin group and deficiency both Yin and Yang group according to symptom and sign of TCM.The relations between picture of tongue,pulse condition and course of disease and symptom and sign of TCM were observed.Results The main part age of patients with T2DM combined with macrovascular complication was 50~70 years old in dryness-heat due to Yin deficiency group.The main part age of patients with T2DM combined with macrovascular complication was above 70 years old in deficiency both Yin and Yang group.There was no significant difference on course of disease among the three groups.The main part of course of disease was three to five years.Red tongue,dry and yellowish fur and string-tight and frequent pulse was the main symptom and sign in dryness-heat due to Yin deficiency group.Red tongue,thin fur and immersing,small and frequent pulse was the main symptom and sign in deficiency both Qi and Yin group.Pale and corpulent tongue,white and greasy fur and sunken,slow and small pulse was the main symptom and sign in deficiency both Yin and Yang group.Conclusion The picture of tongue and pulse condition of T2DM combined with macrovascular complication was in line with the realization of basic theory of TCM to symptom and sign.To analyze the difference and relation symptom and sign of TCM with objective method can preferably discover the essence of symptom and sign of TCM.