宿迁市2007-2009年健康人群流脑抗体水平分析

Analysis on Antibody Level Against Epidemic Cerebrospinal Meningitis in Healthy Population in Suqian from 2007 to 2009

目的了解2007-2009年宿迁市健康人群流行性脑脊髓膜炎A群、C群抗体水平及变化趋势,为制定流脑防控对策提供依据。方法 采集健康人群血清,采用酶联免疫吸附试验(ELISA法)检测流脑A群、C群抗体水平。结果2008年健康人群A群流脑抗体阳性率为73.50%,2007年、2009年A群流脑抗体阳性率均大于75%;2007-2009年健康人群C群流脑抗体阳性率均低于75%,小于3岁的低年龄组抗体阳性率均较低。结论宿迁市存在C群流感暴发或散发的可能,尤其是低年龄组儿童。因此应该加大流脑的防控力度,做好低年龄组儿童A+C流脑疫苗接种工作,保护易感人群,减少流脑的暴发或流行。

Objective To survey the level of antibody to group A and group C epidemic cerebrospinal meningitis and their change tendency among the healthy population in Suqian,and to provide the evidence for making prevention and control measures. Methods The samples of venous blood were collected from healthy people.Enzymelinked immunosorbent assay（ELISA） was used to detect the level of antibody to group A and group C epidemic cerebrospinal meningitis. Results The positive rate of group A antibody was 73.50% in 2008.The positive rates of group A antibody in 2007 and 2009 were both higher than 75%.The positive rates of group C antibody from 2007 to 2009 were all lower than 75%.The positive rates of group A and group C antibody among the children under 3 years old were relatively lower. Conclusions It is predicted that the outbreak or sporadic epidemic of group C cerebrospinal meningitis might happen,especially in low-aged children.Therefore,it is necessary to strengthen the measures for the prevention and control of epidemic cerebrospinal meningitis and improve the inoculation of vaccine against A＋C epidemic cerebrospinal meningitis among low-aged children so as to protect the vulnerable populations and reduce the outbreak or epidemic of cerebrospinal meningitis.