摘要
目的通过分析肝性脊髓病(hepatic myelopathy,HM)的临床发病过程、综合治疗方法,以期做到对该病早期预防、早期治疗。方法回顾性分析19例肝性脊髓病患者的临床特征及治疗过程。结果 15例典型渐进性痉挛性截瘫,2例伴有感觉障碍,9例血氨均升高,5例行脊髓核磁检查未见异常,2例内科治疗双下肢肌力稍好转(12.5%),肝移植3例临床症状明显改善,肝性脊髓病得到控制。结论 HM以双下肢渐进性痉挛性截瘫为主要表现,常规内科治疗效果差,尽早预防,综合治疗延缓病情发展,肝移植为HM治疗带来希望。
Objective To investigate the clinical procedure and combined therapy of hepatic myelopathy and get early-staged perservation and early-staged treatment.Methods To review restropectively 19 cases of HM.Results 15 cases had typical features of progressive spastic parapresis;2 cases had sesnsoy dysfunction,9 cases had a high level of blood ammonia,the spinal cord MRI of 5 cases told nothing abnormal,clinical symptoms of 2 cases accepting routine medicine therapy had slight improvement;3 cases of liver transplantation had a well improvement of clinical symptoms and HM was controlled.Conclusion Progressive spastic paraparesis is the main clinical features of HM.Routine medicine therapy for HM is unsatisfied,while liver transplatation may improve the patient condition,and early-staged perservation and combined therapy can delay the progression of HM.
出处
《实用心脑肺血管病杂志》
2011年第2期278-280,共3页
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
关键词
肝性脊髓病
肝移植
分析
Heaptic myelopathy
Liver transplantation
Analysis
