新达罗治疗泌尿生殖系统感染52例

OBSERVATION OF CLINICAL EFFICACY OF CEFACLOR IN TREATMENT OF URINARY INFECTIONS IN COMPARISON WITH CEFRADINE

目的 :验证国产头孢克罗 (新达罗 )的临床疗效。方法 :5 2例泌尿生殖系统感染患者应用新达罗治疗 ,并与头孢拉定治疗 4 6例进行对照。结果 :治疗组与对照组临床总有效率分别为 92 .3 %和 87% ,其中单纯性泌尿系统感染有效率分别为 10 0 .0 %和 94 .1% ,复杂性尿路感染分别为 90 .5 %和 84 .2 % ,前列腺炎分别为 83 .3 %和80 .0 % ,两组疗效间差异无显著性 (P >0 .0 5 )。治疗组和对照组细菌清除率分别为 88.9%和 82 .9% (P >0 .0 5 ) ,不良反应发生率分别为 5 .8%和 8.7%。结论 :新达罗具有抗菌谱广 ,抗菌活性强 ,尿液浓度高 ,不良反应轻 ,疗效显著等特点 ,对各种泌尿生殖系统感染 ,尤其是轻、中度感染尤为适用。

OBJECTIVE:To validate the clinical efficacy of domestic cefaclor.METHODS:52 patients with urinosexual tract infections were treated with cefaclor in comparison with 46 patients of the same diseases treated with cefradine.RESULTS:The total effective and bacterial eradication rates were 92.3% and 88.9% for active arm and 87% and 82.9%for control arm respectively ,with no significant difference between the two arms in total effective rate.Incidence rates of ADRs were 5.8% for active arm and 8.7% for control arm.CONCLUSION:Cefaclor is effective in treatment of urinosexual tract infection especially mild and moderate urinary infections with mild ADRs.