参芪十一味颗粒治疗白细胞减少的临床观察

Clinical observation of Shenqishiyiwei Granules in treating leukopenia

目的评价参芪十一味颗粒治疗白细胞减少症的临床疗效和安全性。方法 54例白细胞减少症患者随机分为对照组和治疗组。对照组(28例):利血生20 mg,每天3次;鲨肝醇100 mg,每天3次,连用30 d。治疗组(26例):在对照组治疗的基础上,服用参芪十一味颗粒2 g,每天3次,连用30 d。观察两组患者用药前后外周血白细胞计数的变化。结果两组总有效率分别为67.86%和96.15%,差异有统计学意义(P<0.05),均未见明显的不良反应。结论参芪十一味颗粒治疗白细胞减少症有显著疗效,且无明显的不良反应。

Objective To assess the clinical effect and security of Shenqishiyiwei Granules in treating leukopenia.Methods 54 patients with leukopenia were randomly assigned to the treatment group and control group.The control group（n=28）was treated by leucogen 20 mg and batilol 100 mg,3 times daily for 30 d.On the basis of treatment of the control group,the treatment group（n=26）was added with Shenqishiyiwei Granules 2 g,3 times daily for 30 d.The change of WBC count was observed and compared before and after treatment.Results The total effective rate was 67.86% for the control group and 96.15% for the treatment group with statistical difference between the two groups（P0.05）.No obvious side effects were found in both groups.Conclusion Shenqishiyiwei Granules has significant effect in treating leucopenia without remarkable adverse effects.