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AQP-4与脑水肿相互关系的研究现状 被引量：1

Study on Relation between AQP-4 and Celebral Edema
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摘要 AQP4是一种调节脑组织水平衡的通道蛋白。AQP4在分子及基因水平对脑水肿起调控作用,各种病理过程如脑外伤、自发性脑出血、脑肿瘤等导致AQP4的失调控与脑水肿的形成有密切关系。本文就两者关系展开综述。 AQP-4 is a channel protein regulating the balance between brain water.AQP4 regulate the brain edema in the molecular and genetic level.The loss of regulation of AQP4 caused by various pathological processes such as brain trauma,spontaneous intracerebral hemorrhage,and brain tumor is closely related to brain edema formation.This article summed up the relationship the two.
作者 陈泽文 杜贻庆
机构地区 桂林医学院附属医院神经外科
出处 《黑龙江医药》 CAS 2011年第1期71-73,共3页 Heilongjiang Medicine journal
关键词 AQP4 脑水肿 调控机制 AQP-4 cerebral edema regulation
分类号 R741 [医药卫生—神经病学与精神病学]
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参考文献32

  • 1Preston GM,Carroll TP,Cuggino WB,Agre P.Appearance water channels in Xenopus oocytes expressing red cell CHIP28 protein [J].science,1992,256(5055):385-387.
  • 2Liu K,Nagase H,Huang C G,et al.Purification and functional characterization of aquapoim28 [J]. BioCell,2006,98 (3) :153 -161.
  • 3Hasegawa H, Ma T, Skach W,et al. Molecular cloning of a mercurial-insensitive water channel expressed in selected in water transporting tissues [J]. BiolChem, 1994,269 (8) :5497 - 5500.
  • 4MINGQI Lu,M. DOUGLAS LEE,BARBARA L SMITH,et al. The human AQP4 gene: Definition of the locus encoding two water channel polypeptides in brain[J]. Proc Natl Acad Sci USA ,1996,93(20) :10908 - 10912.
  • 5FurmanCS,C, Coerlick - FeldmanDA,DavidsonKG,et al,Aquaporin -4 squaer array assembly:Oppsing actions of M1 and M23 isoforms[J]. Proc Natl Acad Sci USA,2003, 100 (23) : 13609 -13614.
  • 6FrigeriA, GropperM, TurckCW, et al. Immunolocalization of The mercurial -sensitive water channel and glycerol intrinsic Protein in epithelial cell plasma membranes [J]. Proc Nab Acad Sci USA ,1995,9(2) :4328 -4331.
  • 7KingLS Agree Pathophysiology of the aquaporin water channels [J]. Annu Rev Physiol, 1996,58:61 -622.
  • 8Venero JL,Vizuete ML,Machado A,et al. Aquaporins in the Central nervous system[J]. Prog Neurobiol,2001,63 :321 - 336.
  • 9Mardey GT, Fujimura M, Ma T, et al. Aquaporin -4 deletion In mice reduces brain edema after actue water intoxication and ischemic etroke[J]. Nat Meal,2000,6(2) :159 -163.
  • 10石向群,杨金升,张志琳,王运良,包仕尧.水通道蛋白-4在正常大鼠脑内的分布研究[J].中华神经医学杂志,2004,3(4):257-259. 被引量：31

二级参考文献12

  • 1石向群,杨金升,张志琳,王运良,包仕尧.水通道蛋白-4在正常大鼠脑内的分布研究[J].中华神经医学杂志,2004,3(4):257-259. 被引量：31
  • 2Markert JM, Fuller CM, Gillespie GY, et al. Differential gene expression profiling in human brain tumors [J]. Physiol Genomics, 2001, 5(1): 21～33.
  • 3黄强,陈忠平,兰青.胶质瘤[M].北京:中国科学技术出版社,2002.90.
  • 4Verkman AS. Physiological importance of aquaporin water channels [J]. J Biol Chen, 1998, 213: 14659～14662.
  • 5Venero JL,Vizuete ML,Machado A,et al.Aquaporins in the central nervous system[].Progress in Neurobiology.2001
  • 6Vajda Z,Pedersen M,Fuchtbauer EM,et al.Delayed onset of brain edema and mislocalization of aquaporin-4 in dystrophin-null transgenic mice[].Proceedings of the National Academy of Sciences of the United States of America.2002
  • 7Yamamoto N,Sobue K,Miyachi T,et al.Differential regulation of aquaporin expression in astrocytes by protein kinase C[].Molecular Brain Research.2001
  • 8Nagelbus EA,Horio Y,Inanobe A,et al.Immunogold evidence suggests that coupling of K~+ siphoning and water transport in rat retinal Muller cells is medicated by a coenrichment of Kir4. 1 and AQP4 in specific membrane domains[].Glia.1999
  • 9Vajda Z,Promeneur D,Doczi T,et al.Increased aquaporin-4 immunoreactivity in rat brain in response to systemic hyponatremia[].Biochemical and Biophysical Research Communications.2000
  • 10Ken-ichi N,Atsuko F,Mamoru N,et al.A role of the C-terminus of aquaporin 4 in rats membrane expression in cultured astrocytes[].Genes to Cells Devoted to Molecular Cellular Mechanisms.2002

共引文献33

同被引文献13

引证文献1

二级引证文献26

黑龙江医药
2011年 第1期

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