胃食管反流病食管外表现45例临床分析

Extraesophageal Manifestations of Gastroesophageal Reflux Disease:Clinical Analysis of 45 Cases

目的分析以食管外表现为主的胃食管反流病的临床特点。方法对本院门诊及住院的以食管外表现为主的45例胃食管反流病患者的临床表现进行分析,比较确诊前后的治疗效果。结果在本组患者中,食管外表现以慢性咽炎发生率最高。所有病例确诊后经埃索美拉唑药物治疗,总有效率为86.67%,明显高于确诊前40%(P<0.01)。结论对以食管外表现为主诉的胃食管反流病患者,经相应对症治疗疗效差或无效时,应考虑胃食管反流病可能,并作胃镜及食管pH监测,避免误诊。

Objective To analyze the clinical characteristics of gastroesophageal reflux disease mainly with extraesophageal manifestations. Methods Forty-five outpatients and inpatients with gastroesophageal reflux disease mainly with extraesophageal manifestations were analysed and therapeutic effect was compared before and after the definite diagnosis. Results The highest incidence of the extraesophageal disorders was chronic pharyngitis. All the patients received esomeprazole after final diagnosis and the total effective rate was 86.67% , which was significantly higher than that treated before definite diagnosis （40% , P 〈 0. 01 ）. Conclusion When the symptomatic treatment had poor curative effect or was ineffective for the patients with the extraesophageal presentations as chief complaints, the possibility of gastroesophageat reflux disease should be considered and gastroscope examination and esophageal pH monitoring should be used to avoid misdiagnosis.