超分辨率活体人眼视网膜共焦扫描成像系统

Superresolution in adaptive optics confocal scanning laser ophthalmoscope

活体人眼共焦扫描成像系统的分辨率受到人眼像差、数值孔径和探测针孔尺度的限制,本文设计了一套超分辨活体人眼视网膜共焦扫描系统,采用自适应光学技术探测并校正人眼像差,结合光学超分辨技术提高系统分辨率,补偿有限尺度针孔对分辨率的影响,并获得活体人眼的实时、高分辨图像.

The resolution of adaptive optics confocal scanning laser ophthalmoscope is constrained by human eye’s aberration, numberical aperture and pinhole size. A super resolved adaptive optics confocal scanning laser ophthalmoscope is presented. By using adaptive optics to detect and compensate human eye’s aberration,and using optical superresolution to improve resolution which is degraded by large pinhole size,the system can achieve high resolution,real-time human retina image in vivo.