期刊文献+

基于矩阵图谱表达法的蛋白质序列的相似性分析 被引量:2

Similarity analysis of protein sequences based on matrix graphical representation
下载PDF
导出
摘要 在DNA序列的混沌游走方法(CGR)及DNA序列的4线图谱表达方法(4-LGR)的基础上,提出了一种新型DNA序列的表达方法—矩阵图谱表达法(MGR),并进一步,在DNA序列的上述三种表达式基础上,分别推广建立了基于经典HP模型的蛋白质序列的图谱表达法,对蛋白质序列的相似性进行了比较验证。研究表明:矩阵图谱表达方法不仅能够说明蛋白质序列间的相似性,而且与传统的方法相比,该方法更具有灵活性和变通性。 Based on the Chaos Game Representation method(CGR) of DNA sequences and 4 Line Graphical Representation method(4-LGR) of DNA sequences,a novel graphical representation method of DNA sequences—Matrix Graphical Representation(MGR) is proposed.Based on the above three kinds of DNA sequences model,graphical representation of protein sequences is extended based on the detailed HP model respectively.The similarity of protein sequences is compared.The research shows that the method can illustrate the similarity of protein sequences,and is more flexible compared with the traditional method.
出处 《计算机工程与应用》 CSCD 北大核心 2011年第7期222-225,共4页 Computer Engineering and Applications
基金 江南大学创新团队发展计划(PIRTJiangnan)资助 财政部专项"外来物种环境风险评估技术研究"资助
关键词 经典HP模型 混沌游走表达 4线图谱表达 矩阵图谱表达 the detailed Hpmodel Chaos Game Representation(CGR) 4 Line Graphical Representation method(4-LGR) Matrix Graphical Representation(MGR)
  • 相关文献

参考文献7

二级参考文献105

  • 1魏志勇,臧黎慧,李明,范我,许玉杰.射线引起DNA双链断裂的统计分布[J].物理学报,2005,54(10):4955-4960. 被引量:6
  • 2刘小良,徐慧,马松山,邓超生,郭爱敏.DNA分子链的电子局域性质及电导的研究[J].物理学报,2006,55(10):5562-5567. 被引量:10
  • 3Fuchs R.From sequence to biology:the impact on bioinformatics[J]. Bioinformatics, 2002,18 : 505 -506.
  • 4Reichhardt T,It's sink or swim as a tidal wave of data approaches[J].Nature, 1999,399 : 517-520,
  • 5Altschul S F,Madden T L,Schaffer A A,et al.Gapped BLAST and PSIBLAST:a new generation of protein database search programs[J]. Nucleic Acids Res, 1997, 25 : 3389-3402.
  • 6Pearson W R.Rapid and sensitive sequence comparison with FASTP and FASTA[J].Methods Enzymol, 1990,183:63-98.
  • 7Jeffrey H J.Chaos game representation of gene structure[J].Nucleic Acids Res, 1990,18(8)-2163-2170.
  • 8Joseph J,Sasikumar R.Chaos game representation for comparison of whole genomes[J].BMC Bioinformatics, 2006,7( 1 ) : 243.
  • 9Dill K A.Theory for the folding and stability of globular proteins[J]. Biochemistry, 1985,24:1501-1509.
  • 10Chan H S, Dill K A.Compact polymers[J].Macromolecular, 1989,22: 4559--4573.

共引文献37

同被引文献39

  • 1LI W H. Molecular evolution [ M ]. Sunderland: Sinauer Associates Inc Publishers, 1997.
  • 2ABBAS A E, HOLMES S P. Bioinformatics and management science: some common tools and techniques [ J ]. Operations Research, 2004,52(2) :165-190.
  • 3JEFFREY H. Chaos game representation of gene structure[ J ]. Nucle- ic Acids Research,1990,18(8) :2163-2170.
  • 4JUKES T H, CANTOR C R. Evolution of protein molecules[ M]// MUNRO H N. Mammalian Protein Metabolism. New York: Academic Press, 1969:21-132.
  • 5HAMMING R W. Error detecting and error correcting codes [ J]. Bell System Technical Journal, 1950,29 ( 2 ) : 147-160.
  • 6SOKAL R R, MICHENER C D. A statistical method for evaluating systematic relationships [ J ]. University of Kansas Science Bulle- tin, 1958,28:1409-1438.
  • 7FARRIS J S. On the phenetic approach to vertebrate classification [ M]//HECHT M K,GOODY P C, HECHT B M. Major Patterns in Vertebrate Evolution. New York: Plenum, 1977 : 823- 850.
  • 8SATrATH S, TVERSKY A. Additive similarity trees [ J ]. Psy- chometrika, 1977,42 ( 3 ) :319- 345.
  • 9SAITOU N, NEI M. The neighbor-joining method: a new method for reconstructing phylogenetic trees[ J]. Molecular Biology and Evolu- tion, 1987,4 (4) :406-425.
  • 10ECK R V, DAYHOFF M O. Atlas of protein sequence and structure [ M ]. Washington DC: National Biomedical Research Foundation, 1966.

引证文献2

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部