西洛他唑治疗冠心病不稳定型心绞痛67例的临床研究

Clinical Study of Cilostazol on 67 Cases Unstable Angina Pectoris Patients

目的观察在常规治疗的基础上加用西洛他唑治疗不稳定型心绞痛的疗效。方法 134例诊断明确的变异性心绞痛患者被随机分为对照组和治疗组,每组各67例,对照组给予常规治疗,治疗组在对照组的基础上给予西洛他唑50mg口服,每日2次,连续治疗30d后比较两组的临床治疗效果。结果 30d后治疗组的心脏指数改善情况明显优于对照组,两组相比有显著的统计学意义(P<0.05),治疗总有效率为89.55%,对照组总有效率为73.13%,两组相比有显著的统计学意义(P<0.05),治疗组临床疗效明显优于对照组。结论西洛他唑治疗不稳定型心绞痛的临床疗效确切,值得临床推广使用。

Objective To study the clinical effects of Cilostazol on unstable angina pectoris patients. Methods 134 cases unstable angina peetoris patients who were diagnosed to be unstable angina pectoris in our hospital were randomly divided into control group and treatment group,each group 67 patients. The control group was treated with ordinary therapeutical methods. The treatment group received cilostazol 50rag, bid, po, except accepting ordinary therapeutical methods. Two groups all completed a therapeutic period of 30 days. Results （1）The effect of the treatment group compared with the control group has significantly statistics difference （P〈0.05）. （2）Compared back and forth,the treatment group and control group＇s cardiac index all have significantly statistics difference （P〈0.05）; the result of the treatment group compared with that of the control group has also significantly statistics difference（P〈0.05）. Conclusion The therapeutic effect of cilostazol combined with ordinary therapeutical methods on angina pectoris patients is only much better than ordinary therapeutical methods, and worthy of being widely used.