深圳市儿童血清前清蛋白参考范围调查

Investigation on Normal Reference Range for Serum Prealbumin of Healthy Children in Shenzhen Region

目的建立深圳地区健康儿童血清前清蛋白的参考范围。方法应用日立7600全自动生化分析仪对深圳地区3957名健康儿童（男性2667例，女性1290例）的血清前清蛋白（PA）进行检测，对结果进行统计分析。结果PA存在性别差异（P〈0．05）。儿童PA参考范围为男性111．7～281．7mg／L，女性128．4～300．4mg／L。各年龄段的PA参考范围有不同程度的差异，总体PA与年龄呈正相关。结论成人的参考范围不适用于儿童，不同实验室应测定一批健康儿童的标本，统计出本实验室的参考范围，若存在性别差异，应分别制定两性的参考范围，若存在年龄组间差异，还应进一步制定两性间各个年龄组的参考范围。

Objective To establish the normal reference range for serum prealbumin of healthy children in Shenzhen region. Methods Serum prealbumin of 3 957 healthy children （2 667 males,1 290 females） living in Shenzhen region were examined by HITACHI 7600 Automatic Analyzer. Then the data were analysed with statistical methods. Results There was statistical difference between boys and girls for serum prealbumin（P〈0. 05）. The normal reference was 111.7～281.7 mg/L for male and 128.4～300. 4 mg/L for female. There was statistical difference among different age groups. Positive correlation was found between PA value and age. Conclusion Reference range for serum prealbumin of adult is not the same with children. So in different laboratories the normal reference ranges for serum prealbumin ought to be established by sex or by age groups if difference is found after detecting a quantity of healthy children.