大肠埃希菌感染临床分布及耐药性分析

目的:分析医院2007年～2009年大肠埃希菌感染的临床分布特点及耐药性,为临床合理使用抗生素提供科学依据。方法:对392株临床分离的大肠埃希菌的临床分布和药物敏感试验结果进行回顾性分析。结果:大肠埃希菌感染的部位主要见于呼吸道、泌尿道、创面分泌物、血液等,大肠埃希菌耐药性较低的抗生素有亚胺培南、阿米卡星、哌拉西林/他唑巴坦(耐药率<14%),对氟喹诺酮类及头孢菌素类耐药率较高。结论:目前临床分离大肠埃希菌耐药率和耐药性逐渐增加,应根据药敏结果及患者病情合理选用碳青酶烯类、氨基糖苷类等抗生素。

Objective：To investigate the hospital in 2007 and 2009 distribution of E.coli infection and antibiotic resistance,antibiotics for clinical use to provide a scientific basis.Methods：392 clinical isolates of Escherichia coli clinical distribution and drug susceptibility testing results were analyzed retrospectively.Results：E.coli infections were mainly seen in parts of the respiratory tract,urinary tract,wound secretions,blood,etc;Escherichia coli antibiotic resistance in the lower imipenem,amikacin,piperacillin / tazobactam resistance rates 14%;to fluoroquinolones and cephalosporins resistance is higher.Conclusion：The clinical isolates of E.coli resistance rates and drug resistance Yin gradually increased,should be based on susceptibility results and the patient＇s condition a reasonable selection of Carbapenems,aminoglycosides and other antibiotics.