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原发性开角型青光眼基因基础研究 被引量:1

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摘要 POAG是一种复杂的,变异性疾病,以视网膜的特定区域的视网膜神经节细胞(RGCs)及其轴突的逐步退化为特点,视网膜神经节细胞和其轴突的丢失导致其相应神经支配区域的视野缺陷,从而造成视功能不可逆性丧失。有文献报道青光眼已成为全球第2大致盲眼病。
作者 张娴 袁援生
出处 《当代医学》 2011年第8期37-38,共2页 Contemporary Medicine
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参考文献16

  • 1Kass MA. Heuer DK.Higginbotham E, et al. The Ocular Hypertension Treatment Study, a randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucoma[J]. Arch Ophthalmol, 2002, 6(120): 701-713.
  • 2Quigley H.Open-angle glaucoma[J].NEnglJMed 1995,528.1097-1106.
  • 3Quigley HA, Broman AT. The number Of people with glaucoma worldwide [J].Br J Ophthalmol,2001, 80: 389-393.
  • 4FuseN,Miyazawa A,TakahashiK,et al.(2010)Mutation Spectrum of CYPlBl Gene for Congenital Glaucoma in the Japanese Population.Jpn. J Ophthalmol,2010,54.1-6.
  • 5Mabuchi F,T&ng S,Keshiwagi K,et al.The OPAl gene polymorphsm is associsted with normal tension srid high tension glsucoma[J].Am J Ophthslmol 2007,143.125-130.
  • 6Suri F, Kalhor R,Zargar SJ,et al.Screening of common CYPlBl mutations in iranian POAG patients using a microarraybased PrASE protocol. Mol Vis[EB/OL].2008,14:56-2349.Available at:http://www.molvis.org/molvis/ v14/a271/. Accessed April 19,2009.
  • 7田强,李富华,赵堪兴,王立,单晓艳,庞玉英,李袆馨,吴梅筠,邱枫,李海云.原发性开角型青光眼家系一新的myocilin基因突变[J].中华医学遗传学杂志,2007,24(6):629-634. 被引量:9
  • 8Bayat B,Yazdani S,Alavi A,et al.Oontributions of MYOC and CYPlBl mutations to JOAG.Mol Vis [EB/OL] 2008,14.17-508 Available at:http://www. molvis.org/molvis/v14/a61/.Accessed April 19,2009.
  • 9Sarfarazi M,Rezaie T.Optineurin in primary open angle glaucoma[J].Ophthalmol Olin North Am,2005,16(4).529-541.
  • 10Whitelaw E,Martin Dl.Retrotransposons as epigenetic mediators of phenotypic variation in mammals[J].Nat Genet,2001,27.361-365.

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同被引文献6

  • 1Filla MS, Schwinn MK, Sheibani N, et al. Regulation of cross-linked actin network (CLAN) formation in human trabecular meshwork ( HTM ) cells by convergence of distinct betal and beta3 integrin pathways. Invest Oph- thalmol Vis Sci, 2009,50:5723-5731.
  • 2Faralli JA,Schwinn MK, Gonzalez JM Jr,et al. Functional properties of fi- bronectin in the trabecular meshwork. Exp Eye Res,2009,88:689-693.
  • 3Peterson JA, Peters DM. Heparin II (Hepll) domain of fibronectin modu- lates rho mediated events in proliferating human trabecular meshwork (HTM) cells via ct41 lntegrin. Invest Ophthalmol Vis Sci,2004,45:E- Abstract 4369.
  • 4Schwinn MK,Gonzalez JM Jr, Gabeh BT, et al. Hepaxin II domain of fi- bronectin mediates contractility through an alpha4betal co-signaling path- way. Exp Cell Res,2010,316:1500-1512.
  • 5Faxalli JA, Peters JM, Newman JR, et al. Effect of heparin II domain of fi- bronectin on actin cytoskeleton and adherens junctions in human trabecu- lax meshwork cells. Invest Ophthalmol V is Sci,2006,47:2924-2931.
  • 6李高坚.青光眼的临床研究进展与发展趋势[J].当代医学,2012,18(10):21-22. 被引量:8

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