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右美托咪定对脑动脉瘤手术全麻诱导、气管插管和安置头架时血流动力学的影响 被引量:11

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摘要 目的观察右美托咪定对脑动脉瘤手术全麻诱导、气管插管和安置头架时血流动力学的影响。方法脑动脉瘤夹闭术、需安置头架患者40例,随机分为右美托米啶(D)组和对照(C)组。D组在15min内静脉泵注1μg/kg右美托咪定,C组输注等容量生理盐水。观察用药前(T0)、用药后(T1)、气管插管前(T2)、气管插管后(T3)、安置头架前(T4)和安置头架后(T5)各时点SBP、DBP、MAP和HR值。结果 D组T0~T3各时点间及T4和T5时点间,SBP、DBP和MAP无统计学差异(P>0.05),T1~T5各时点HR无统计学差异(P>0.05),均明显低于T0时点(P<0.01)。C组T2时点SBP、DBP和MAP明显低于T1和T3时点(P<0.01),T2时点HR明显低于T3时点(P<0.01),T4时点SBP、DBP、MAP和HR明显低于T5时点(P<0.01)。结论右美托咪定是脑动脉瘤手术良好的麻醉辅助药。
作者 张艳梅 金强
出处 《当代医学》 2011年第8期53-54,共2页 Contemporary Medicine
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