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局限期小细胞肺癌放射治疗的相关研究 被引量：4

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摘要 肺癌的发生率和死亡率占城市恶性肿瘤之首位，其中小细胞肺癌（small cell lung cancer，SCLC）约占15％-20％，其生物学行为及临床特点与其他类型肺癌不同，主要表现为癌细胞倍增时间短、侵袭性强、分化程度低、较早出现远处转移、预后较差，但对放疗及化疗均很敏感，而近30年来的研究表明：SCLC是所有治疗敏感的肿瘤中最难治愈的一种。
作者 张世琳(综述) 徐向英(审校)
机构地区 哈尔滨医科大学附属第三医院 黑龙江省肿瘤防治研究所
出处 《实用肿瘤学杂志》 CAS 2011年第1期87-90,共4页 Practical Oncology Journal
关键词 小细胞肺癌 局限期 放射治疗
分类号 R734.2 [医药卫生—肿瘤]
  • 相关文献

参考文献19

  • 1Govindan R, Page N, Morgensztern D, et al. Changing epide- miology of small - cell lung cancer in the United States over the last 30 years : analysis of the surveillance, epidemiologic, and end results database[ J ]. J Clin Oncol,2006,24 ( 28 ) : 4539 - 4544.
  • 2胡晓,包勇,张力,陈媛媛,李凯新,王卫华,刘源,何瀚,孙宗文,庄婷婷,王彦,陈静,梁颖,张阳,赵洪云,王凤华,陈明.局限期小细胞肺癌放疗靶区前瞻性随机对照研究的初步报告[J].中国肺癌杂志,2010,13(7):691-699. 被引量：7
  • 3De Ruysscher D, Bremer RH, Koppe F, et al. Omission of e- lective node irradiation on basis of CT - scans in patients with limited disease small cell lung cancer:A phase I1 trial[ J ]. Radiother Onco1,2006,80 ( 3 ) :307 - 312.
  • 4Videtic GM, Belderbos JS, Spring Kong FM, et al. Report from the International Atomic Energy Agency (IAEA)con- sultantsineeting on elective nodal irradiation in lung cancer: small -cell lung cancer(SCLC) [ J]. Int J Radiat Oncol Bi- ol Phys ,2008 ,72 ( 2 ) : 327 - 334.
  • 5Miller AA, Wang XF, Bogart JA, et al. Phase II trial of pa- clitaxel- topotecan -etoposide followed by consolidation chemoradiotherapy for limited - stage small cell lung canc- er: CALGB 30002 [ J ]. J Thorae Oncol, 2007,2 ( 7 ) : 645 - 651.
  • 6Faivre - Finn C, Falk S. CONVERT : concurrent once - daily versus twice - daily radiotherapy - a new phase HI random- ized controlled trial for patients with limited - stage small cell lung cancer and good performance status [ J ]. Lung Cancer, 2009,63 (2) : S 12.
  • 7Turrisi AT, Kim K, Blum R, et al. Twice - daily compared with once -daily thoracic radiotherapy in limited small- cell lung cancer treated concurrently with cisplatin and eto- poside[ J]. N Engl J Med,1999,340(4) :265 -271.
  • 8Natsuo T, Takeshi K,Toyoaki H, et al. The impact of radia- tion dose and fractionation on outcomes for limited - stage small -cell lung cancer [ J ]. Int J Radiat Oncol Biol Phys, 2010,76(4) :1121 - 1126.
  • 9Takada M, Fukuoka M, Kawahara M, et al. Phase III study of concurrent versus sequential thoracic radiotherapy in combi- nation with cisptatin and etoposide for limited - stage small -cell lung cancer: results of the Japan Clinical Oncology Group Study 9104 [ J ]. J Clin 0ncol,2002,20 ( 14 ) : 3054 - 3060.
  • 10Bogart JA, Hemdon JE, Lyss AP, et al. 70Gy thoracic ra- diotherapy is feasible concurrent with chemotherapy for limited- stage small- cell lung cancer: analysis of Cancer and Leukemia Group B study 39808 [ J ]. Int J Radiat On- col Biol Phys,2004,59(2) :460 -468.

二级参考文献37

  • 1Faivre-Finn C, Lorigan P, West C, et al. Thoracic radiation radiotherapy for limited-stage small-cell lung cancer: unanswered questions. Clin Lung Cancer, 2005, 7(1): 23-29.
  • 2Pignon JP, Arriagada R, Idhe D, et al. A meta-analysis of thoracic radiotherapy for small-ceU lung cancer. N EnglJ Med, 1992, 327(23): 1618-1622.
  • 3Warde P, Payne D. Does thoracic irradiation improve survival and local control in limited-stage small-cell lung cancer. J Clin Oncol, 1992, 10(6): 890-895.
  • 4Sundstrom S, Bremnes RM, Kaasa S, et al. Cisplatin and etoposide regimen is superior to cyclophosphamide, epirubicin, and vincristine regimen in small-cell lung cancer: results from a randomized phase III trial with 5 years' follow-up.J Clin Oncol, 2002, 20(24): 4665-4672.
  • 5Turrisi AT 3rd, Kim K, Blum R, et al. Twice-daily compared with once-daily thoracic radiotherapy in limited small-cell lung cancer treated concurrently with cisplatin and etoposide. N EnglJ Med, 1999, 340(4): 265-267.
  • 6Schild SE, Bolmer JA, Hillman S, et al. Results of a phase II study of highdose thoracic radiation therapy with concurrent cisplatin and etoposide in limited-stage small-cell lung cancer (NCCTG 95-20-53).J Clin Oncol, 2007, 25(21): 3124-3129.
  • 7Baas P, Belderbos JS, Senan S, et al. Concurrent chemotherapy (carboplatin, paclitaxel, etoposide) and involved-field radiotherapy in limited stage small cell lung cancer: A Dutch multicenter phase II study. Br J Cancer, 2006, 94(5): 625-630.
  • 8Spiro SG, James LE, Rudd RM, et al. London Lung Cancer Group. Early compared with late radiotherapy in combined modality treatment for limited disease small-cell lung cancer: A London Lung Cancer Group multicenter randomized clinical trial and meta-analysis. J Clin Oncol, 2006, 24(24): 3823-3830.
  • 9Chen GY, Jiang GL, Wang LJ, et al. Cisplatin/etoposide chemotherapy combined with twice daily thoracic radiotherapy for limited small-cell lung cancer: a clinical phase II trail. Int J Radiat Oncol Biol Phys, 2005, 61 (1): 70-75.
  • 10Bogart JA, Herndon JE, Lyss AP, et al. 70 Gy thoracic radiotherapy is feasible concurrent with chemotherapy for limited-stage small-cell lung cancer: Analysis of Cancer and Leukemia Group B study 39808. Int J Radiat Oncol Biol Phys, 2004, 59(2): 460-468.

共引文献7

同被引文献32

  • 1刘艳,黎星,贾志强,赵峰.51例小细胞肺癌的CT表现及病理诊断特点分析[J].新疆医科大学学报,2005,28(3):262-263. 被引量：9
  • 2蒋国梁.原发性肝癌治疗的新方法——三维适形放疗[J].癌症进展,2006,4(4):279-283. 被引量：39
  • 3宁尚峰.中央型小细胞肺癌的CT诊断[J].华西医药,2008,23(6):1384-1385.
  • 4National Cancer Institute (NCI). NCI website, lung cancer homepate[ EB/OL]. http ://www. cancer, gov/cancertopics/ types/lung.
  • 5Micke P, Basrai M, Faldum A, et al. Characterization of e - kit expression in small cell lung cancer:Prognostic and ther- apeutic implication [ J ]. Clin Cancer Res, 2003,9 : 188 - 194.
  • 6Qiu FH, Ray P, Brown K, et al. Primary structure of c - kit : relationship with the CSF- I/PDGF receptor kinase family - oncogenic activation of v - kit involves deletion of extra- cellular domain and C terminus [ J ]. EMBO J, 1988,7 (4) : 1003 - 1011.
  • 7Zhang M, Ma Q, Hu H, et al. Stem ceil factor/c -kit singali- ng enhances invision of pancreatic cancer cells via HIF - 1 alpha under normoxie condition [ J 1- Cancer Lett, 2011,303 (2) :108 - 117.
  • 8Hitoshi K,Tohru T, Itaru M, et al. Neoplastic transformation of normal hematopoietic ceils by constitutively activating mutations of c - kit receptor tyrosine kinase [ J]. Blood, 1996,88 (3) :995 - 1004.
  • 9Miettinen M, Lasota J. KIT( CD117):A review on expres- sion in normal and neoplasttic tissues, and mutations and their elinicopaththologie correlation [ J ]. Appl Immunohisto- chem Mol Morpho1,2005,13 ( 3 ) :205 - 220.
  • 10Naeem M, DahiyaM, Clark JI, et al. Analysis of c - kit pro- tein expression in small cell lung carcinama and its implica-tion for prognosisE J]. Hum Pathol,2002,33 (12) 1182 - 1187.

引证文献4

二级引证文献17

实用肿瘤学杂志
2011年 第1期

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